Scientific Reports
April 21, 2026
Rong Ding, Daojie Wang, Guoxin Wang et al.
Elderly colorectal cancer (CRC) patients face high risks of postoperative depression state, inadequately addressed by opioid-based analgesia. Esketamine, an NMDA receptor antagonist with rapid antidepressant effects, offers potential benefits but lacks evidence in this population. This double-blind RCT enrolled 99 elderly (≥ 65 years) CRC resection patients, randomized to three postoperative...
Mindfulness
August 28, 2025
Fang Fei Lyu, Vimala Ramoo, Ping Lei Chui et al.
Exercise has known benefits for bone, physical, and mental health. This study aimed to determine the effects of a tailored mindful exercise program on back pain, balance, kinesiophobia, mindfulness, anxiety, and depression in older patients with primary osteoporosis. A two-arm randomized controlled trial (RCT) was conducted in a hospital setting in Kunming, China. Eligible patients were...
Reviews in cardiovascular medicine
August 1, 2024
Jifa Tao, Xingkui Dou, Lixing Chen et al.
4 citations
Acute coronary syndrome (ACS) poses a significant threat to health and well-being, although percutaneous coronary intervention (PCI) is an effective treatment method. However, many patients undergoing PCI for coronary heart disease often experience negative emotions such as depression and anxiety, as well as sleep disturbances, poor adherence to medications, and somatic symptoms. These adverse...
Shixia Xu, Jiaojiao Yang, Jing Li et al.
preprint
Abstract Background Postpartum depression (PPD) is a common mental disease in postpartum women, which has received more and more attention in society. Ketamine has been confirmed for its rapid antidepressant effect in women with PPD. We speculate that esketamine, an enantiomer of ketamine, pretreatment during cesarean can also reduce the incidence of PPD. Methods All the parturients enrolled in...