Scientific ReportsApril 21, 2026Rong Ding, Daojie Wang, Guoxin Wang et al.
Elderly colorectal cancer (CRC) patients face high risks of postoperative depression state, inadequately addressed by opioid-based analgesia. Esketamine, an NMDA receptor antagonist with rapid antidepressant effects, offers potential benefits but lacks evidence in this population. This double-blind RCT enrolled 99 elderly (≥ 65 years) CRC resection patients, randomized to three postoperative...
MedicineJuly 11, 2025Liyuan Fu, Minghui Mao, Chengkun Hong et al.
This study evaluates the influence of solution-focused approaches combined with mindfulness-based stress reduction (MBSR) on claustrophobia in a high-risk cohort undergoing magnetic resonance (MR) imaging. In the prospective observational 2-group study, a total of 77 patients (55% male, mean age 50.1 ± 11.9) underwent solution-focused brief therapy (SFBT) and MBSR before MR examination. The...