5 papers in the library · 48 citations · publishing 2017-2023
New Journal of Chemistry 2023 Bronislav Jurásek, Patrik Fagan, Bohumil Dolenský et al. 6 citations
Methoxphenidine was originally patented for its properties to treat neurotoxic injury.
Pharmaceuticals November 30, 2022 Martin Paškan, Silvie Rimpelová, Vladimíra Svobodová Pavlíčková et al. 9 citations
New psychoactive substances and among them synthetic cathinones represent a significant threat to human health globally. However, within such a large pool of substances derived from a natural compound ((S)-cathinone), substances with important pharmaceutical uses can be identified, as already documented by bupropione. Therefore, this work aimed to find a synthetic pathway for a novel synthetic...
British Journal of Pharmacology 2022 Kristýna Štefková-mazochová, Hynek Danda, Wim Dehaen et al. 13 citations
Deschloroketamine (DCK), a structural analogue of ketamine, has recently emerged on the illicit drug market as a recreational drug with a modestly long duration of action. Despite it being widely used by recreational users, no systematic research on its effects has been performed to date. Pharmacokinetics, acute effects, and addictive potential in a series of behavioural tests in Wistar rats...
New Journal of Chemistry 2018 Bronislav Jurásek, František Králík, Silvie Rimpelová et al. 15 citations
Deschloroketamine has been synthesized, the absolute configuration of enantiomers elucidated and the in vitro cytotoxicity of the enantiomers determined using nine different cell lines.
Powder Diffraction June 21, 2017 J. Maixner, Bronislav Jurásek, Michal Kohout et al. 5 citations
X-ray powder diffraction data, unit-cell parameters, and space group for S -2-(methylamino)-2-phenylcyclohexan-1-one hydrochloride, C 13 H 18 ClNO, are reported [ a = 6.578 (1) Å, b = 13.250 (2) Å, c = 15.096 (2) Å, β = 91.619 (3)°, unit-cell volume V = 1315(1) Å 3 , Z = 4, and space group P 2 1 ]. All measured lines were indexed and are consistent with the P 2 1 space group. No detectable...