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Kristýna Štefková-mazochová

2 papers in the library · 16 citations · publishing 2022-2025

Papers

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The acute effects of methoxphenidine on behaviour and pharmacokinetics profile in animal model.

Progress in Neuro-Psychopharmacology and Biological Psychiatry March 20, 2025 Kristýna Štefková-mazochová, Hynek Danda, Vladimír Mazoch et al. 3 citations

Methoxphenidine (MXP) is classified as a new psychoactive substance that has recently emerged on the illicit drug market. Understanding the pharmacological and behavioural profiles of newly emerging drugs is essential for a better understanding of their psychotropic effects and potential toxicity. Therefore, in this study, we investigated a broad range of effects of acute MXP administration:...

DOI: 10.1016/j.pnpbp.2025.111285 (opens in new tab) Full text (opens in new tab) Methoxphenidine Pharmacokinetics Systemic toxicity Wistar rats +7

Pharmacokinetic, pharmacodynamic, and behavioural studies of deschloroketamine in Wistar rats.

British Journal of Pharmacology 2022 Kristýna Štefková-mazochová, Hynek Danda, Wim Dehaen et al. 13 citations

Deschloroketamine (DCK), a structural analogue of ketamine, has recently emerged on the illicit drug market as a recreational drug with a modestly long duration of action. Despite it being widely used by recreational users, no systematic research on its effects has been performed to date. Pharmacokinetics, acute effects, and addictive potential in a series of behavioural tests in Wistar rats...

DOI: 10.1111/bph.15680 (opens in new tab) Full text (opens in new tab) Nmda receptor Deschloroketamine Enantiomers Locomotion +2