Neuroscience Applied
September 1, 2026
Carolina Seybert, Ana Matos Pires, Luís Madeira et al.
The therapeutic benefits of psychedelics for neuropsychiatric conditions have gathered significant attention in Europe and around the world, with treatments using psilocybin, MDMA, and ketamine as notable examples. However, the mind-altering effects of these substances, and the complexity of their regulatory frameworks, both within and outside of therapeutic use, imply careful clinical...
Psychopathology
2025
Stefan Jerotić, Janko Nešić, Vuk Vuković et al.
3 citations
Psychopharmacology is currently plagued by reductionism since it is understood as the treatment of biological and behavioural symptoms of mental disorders without taking into account the subjective life of the self in relation to others. Psychopharmacological interventions, such as antidepressants and antipsychotics, must be situated and discussed within the embodied context of the...
Philosophies
August 24, 2023
Nuno Azevedo, Miguel Oliveira Da Silva, Luís Madeira
11 citations
Background: Psychedelics are known for their powerful mental effects due to the activation of 5HT-2A receptors in the brain. During the 1950s and 1960s, research was conducted on these molecules until their criminalization. However, their clinical investigation as therapeutic tools for psychiatric disorders has revived the deontological ethics surrounding this subject. Questions arise as...
Schizophrenia Research
September 1, 2019
Luís Madeira, Elizabeth Pienkos, Teresa Filipe et al.
18 citations
A disturbance of "minimal self," - of the immediate sense of mine-ness inherent in experience-is hypothesized to be the core disturbance in schizophrenia. Research with the Examination of Anomalous Self Experience (EASE) has demonstrated the selective aggregation of anomalous self-experiences in the schizophrenia spectrum. Conceptual research suggests that anomalous world experiences, including...
Psychopathology
2017
Luís Madeira, Sergio Carmenates, Cristina Costa et al.
31 citations
Anomalous self-experiences (ASEs), presumably involving alterations in "core" or "minimal self," have been studied as manifest in schizophrenia and its spectrum, in contrast with mood disorder and personality disorder samples. This is the first study to examine ASEs in panic disorder (PD), beginning the exploration of these disturbances of subjectivity in anxiety disorders. We aimed to clarify...