Current frameworks for machine consciousness—notably Integrated Information Theory (IIT) and Global Workspace Theory (GWT)—suffer from either computational intractability or unfalsifiability, rendering them unsuitable as operational safety criteria for artificial general intelligence (AGI). We propose the ZQCM framework, which formulates consciousness as a non‑equilibrium topological phase...
The use of tourniquets (TQ) during the total knee arthroplasty (TKA) induced ischemia-reperfusion (I/R) injury in the limb, resulting in the release of inflammatory cytokines and reactive oxygen species (ROS), therefore leading to myocardial damage. This study aimed to investigate the effects and molecular mechanism of Esketamine on myocardial injury (MI) caused by TQ-induced I/R injury. A...