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Effects of a online brief modified mindfulness-based stress reduction therapy for anxiety among Chinese adults: A randomized clinical trial.

Minghuan Wang, Han Zhang, Xiaofan Zhang, Qian Zhao, Jing Chen, Caihong Hu, Renjie Feng, Denghua Liu, Peicai Fu, Chenyan Zhang, Jie Cao, Jianrong Yue, Haihang Yu, Hongxia Yang, Biting Liu, Wanting Xiong, Huiqi Tong, Suiqiang Zhu, Yuan Yang

Journal of Psychiatric Research May 2023 DOI: 10.1016/j.jpsychires.2023.03.009 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Randomized controlled trial Peer reviewed
Sample size 150
Population Adults with anxiety symptoms from the general population
Interventions Modified mindfulness-based stress reduction (mMBSR) Cognitive-behavioral therapy (CBT)
Duration 6 sections in 3 weeks; assessments at baseline, post-treatment, and 6 months post-treatment
Measures Generalized Anxiety Disorder-7, Patient Health Questionnaire-9, Patient Health Questionnaire-15, Cohen Perceived Stress scale, Insomnia Severity Index, Snaith-Hamilton Pleasure Scale
Topics Anxiety Meditation
Keywords Anxiety disorders Cognitive-behavioral therapy Mental health Randomized clinical trial
Key findings The authors report that an online brief modified mindfulness-based stress reduction program significantly improved anxiety, depression, somatization, stress, insomnia, and pleasure scores compared with a waitlist group, with benefits persisting at 6 months and showing no significant difference from cognitive-behavioral therapy.

Abstract

The COVID-19 pandemic has exacerbated anxiety and related symptoms among the general population. In order to cope with the mental health burden, we developed an online brief modified mindfulness-based stress reduction (mMBSR) therapy. We performed a parallel-group randomized controlled trial to evaluate the efficacy of the mMBSR for adult anxiety with cognitive-behavioral therapy (CBT) as an active control. Participants were randomized to mMBSR, CBT or waitlist group. Those in the intervention arms performed each therapy for 6 sections in 3 weeks. Measurements were conducted at baseline, post-treatment and 6 months post-treatment by Generalized Anxiety Disorder-7, Patient Health Questionnaire-9, Patient Health Questionnaire-15, reverse scored Cohen Perceived Stress scale, Insomnia Severity Index, and Snaith-Hamilton Pleasure Scale. 150 participants with anxiety symptoms were randomized to mMBSR, CBT or waitlist group. Post intervention assessments showed that mMBSR improved the scores of all the six mental problem dimensions (anxiety, depression, somatization, stress, insomnia, and the experience of pleasure) significantly compared to the waitlist group. During 6-month post treatment assessment, the scores of all six mental problem dimensions in the mMBSR group still showed improvement compared to baseline and showed no significant difference with the CBT group. Our results provide positive evidence for the efficacy and feasibility of an online brief modified MBSR program to alleviate anxiety and related symptoms of individuals from the general population, and the therapeutic benefits of mMBSR persisted for up to six months. This low resource-consuming intervention could facilitate the challenges of supplying psychological health therapy to large scale of population.

Comparable studies

Other randomized controlled trials on anxiety, most cited first.

Study Year Design Participants
Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients 2000 Randomized controlled trial n = 145
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial Cancer patients with life-threatening diagnoses and symptoms of depression and/or anxiety 2016 Randomized controlled trial n = 51
Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial Patients with cancer-related anxiety and depression 2016 Double-blind, placebo-controlled, crossover trial n = 29
Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance Hallucinogen-naïve adults reporting regular participation in religious or spiritual... 2006 Double-blind study n = 36
Pilot Study of Psilocybin Treatment for Anxiety in Patients With Advanced-Stage Cancer Adults with advanced-stage cancer and anxiety 2010 Double-blind, placebo-controlled study n = 12

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