Auditory Hallucinations and the Brain’s Resting-State Networks: Findings and Methodological Observations
Schizophrenia Bulletin June 8, 2016 Ben Alderson-Day, Kelly Diederen, Charles Fernyhough et al. 134 citations
Resting-state brain networks may help explain hallucinations across different sensory modalities and populations. This report from the International Consortium on Hallucination Research reviews evidence linking resting-state alterations to auditory hallucinations, finding connectivity differences in left-hemisphere auditory and language regions, plus atypical interactions of the default mode network with networks for cognitive control and salience. Similar patterns appear in visual hallucinations, suggesting both domain-general and modality-specific network changes. However, high methodological heterogeneity across studies limits direct comparisons. The authors offer recommendations for future research on resting-state connectivity and hallucinations.