Whether propofol-induced loss of consciousness (LOC) reflects a single thalamocortical transition or involves temporally dissociable local and interregional dynamics remains unclear. Using stereo-electroencephalography recordings from the anterior nucleus of the thalamus, prefrontal cortex, and temporal cortex during anesthesia induction, we quantified permutation entropy, spectral power,...
Background: Brainstem reticular formation (BRF) is crucially involved in regulating arousal, making it a potential target for reversing general anesthesia. The transnasal approach provides a minimally invasive access to the ventral brainstem. However, whether this approach can effectively modulate arousal remains unknown. Objective: To evaluate the efficacy of transnasal BRF electrical...
The authors present a case of an out-of- body experience (OBE) that occurred in a child with intractable epilepsy when stimulating the anterior insular cortex (AIC) by intracranial electrodes. After destroying several sites precisely located at the left AIC by radiofrequency thermocoagulation, the patient's seizures disappeared, and the OBE could not be reproduced when repeatedly stimulating...