The search for neurophysiological markers of consciousness and their neural substrates remains a focal point in neuroscience research. The integrated information theory (IIT) provides a promising quantitative framework for consciousness assessment, but computational limitations of existing Φ estimation methods hinder an in-depth understanding of large-scale cortical integration. Here, we...
Identifying the state-related "neural correlates of consciousness" for anesthetics-induced unconsciousness is challenging. Spatiotemporal complexity is a promising tool for investigating consciousness. The authors hypothesized that spatiotemporal complexity may serve as a state-related but not drug-related electroencephalography (EEG) indicator during an unconscious state induced by different...
Information integration and network science are important theories for quantifying consciousness. However, whether these theories propose drug- or conscious state-related changes in EEG during anaesthesia-induced unresponsiveness remains unknown. A total of 72 participants were randomised to receive i.v. infusion of propofol, dexmedetomidine, or ketamine at a constant infusion rate until loss...