Molecular Psychiatry
April 13, 2026
Xin Zhao, Xinyu Zhang, Shiying Yuan et al.
Ketamine, a potent N-methyl-D-aspartate receptor (NMDAR) antagonist, is widely used for anesthesia and analgesia and, because of its rapid antidepressant effects, in psychiatry. Increasing evidence suggests that ketamine and its enantiomers-(R)-ketamine (arketamine) and (S)-ketamine (esketamine)-also modulate systemic immunity and provide organ protection, partly through interactions with the...
Biological Psychology
2026
Xiaonan Zhan, Huibiao Li, Ke Chen et al.
Depression constitutes a major global public health burden, with university students exhibiting a disproportionately high prevalence of depressive symptoms. Although Mindfulness-Based Stress Reduction (MBSR) has demonstrated efficacy in alleviating depressive symptomatology, its underlying neurobiological mechanisms remain incompletely understood. This randomized controlled trial investigated...
Stress and health : journal of the International Society for the Investigation of Stress
August 1, 2025
Jianhao Zhou, Xin Zhao, Cheng Fan et al.
2 citations
Resilience helps mitigate the negative impacts of stress and promotes effective adaptation in adverse situations. This study investigated the impact of immediate and standardized mindfulness meditation (MM) on the resilience of college students, aiming to offer adaptable MM practices for different stress scenarios. The blood pressure (BP) and heart rate variability (HRV) of 48 participants were...
Scientific Reports
February 19, 2025
Xue Zhang, Xin Zhao, Jiaxin Xu et al.
8 citations
Emergency endotracheal intubation in critically ill patients are dangerous procedures with a greater risk of severe hypotension The efficacy and safety of esketamine with sympathoexcitatory effects for rapid sequence induction in critically ill patients remain unclear. In this prospective double-blinded randomized controlled trial, adult patients were randomly assigned to receive either...
Neuroscience and Biobehavioral Reviews
July 1, 2024
Cheng Fan, Mengjiao Wu, Hong Liu et al.
This systematic review investigates the impact of meditation on neural responses to pain, as measured by functional magnetic resonance imaging (fMRI). Up to March 2024, we conducted searches across four databases for human studies implementing fMRI to assess the efficacy of meditation for pain relief. Eighteen studies met the inclusion criteria. Our systematic review indicates that activation...