Depression constitutes a major global public health burden, with university students exhibiting a disproportionately high prevalence of depressive symptoms. Although Mindfulness-Based Stress Reduction (MBSR) has demonstrated efficacy in alleviating depressive symptomatology, its underlying neurobiological mechanisms remain incompletely understood. This randomized controlled trial investigated...
This study aims to explore the temporal dynamics of the relationships between problematic social media use(PSMU), self-transcendence values, and school adaptation among college students.Methods This study employed longitudinal cross-lagged analysis and structural equation modeling to investigate whether there is a mutual influence among PSMU, self-transcendence values, and school adaptation....
The purpose of the present study was to investigate whether ketamine's rapid antidepressant effects were associated with its anti-inflammatory actions and to explore the underlying molecular mechanism. Depressive-like behaviors was induced in mice using chronic restraint stress (CRS) method. Anti-depressive effects of ketamine were evaluated by forced swimming tests (FST) and sucrose preference...