Margy Y. Chen

2 papers in the library · publishing 2025

Papers

Mode matters: exploring how modes of cannabis administration affect THC plasma concentrations and subjective effects

Journal of Cannabis Research May 23, 2025 Margy Y. Chen, Ashley Brooks-Russell, Angela D Bryan et al.

Dabbing, a method of vaporizing cannabis concentrates, produces higher blood THC concentrations and stronger subjective drug effects than smoking flower products via joints or bongs, though the intense intoxication fades more quickly. Vaping also shows a rapid decline in subjective effects. These findings come from a secondary analysis of two quasi-experimental studies with 252 participants who used their own legal-market cannabis products in a naturalistic setting. The results highlight that the mode of administration substantially influences THC exposure and the experience of intoxication, and future research should account for these differences.

DOI: 10.1186/s42238-025-00282-y Full text Medicine Psychology

Investigating the Relationship Between Cannabis Expectancies and Anxiety, Depression, and Pain Responses After Acute Flower and Edible Cannabis Use.

Cannabis and Cannabinoid Research February 1, 2025 Margy Y. Chen, Emily B Kramer, Laurel P Gibson et al.

People who expect cannabis to improve their health tend to report greater acute reductions in tension after smoking cannabis flower, and greater increases in elation and reductions in pain after eating cannabis edibles. Among edible users, expecting cannabis to help with depression was linked to more elation, and expecting it to help with pain was linked to less pain. These expectancy effects occurred regardless of the product's THC and CBD levels, showing that users' beliefs shape some of the subjective effects of legal cannabis.

DOI: 10.1089/can.2023.0264 Full text Anxiety Cannabis Depression Expectancy +2