Frontiers in Psychiatry
April 24, 2018
Rachel R. Horsley, Eva Lhotková, Kateřina Hájková et al.
20 citations
3,4-methylenedioxypyrovalerone (MDPV) is a potent pyrovalerone cathinone that is substituted for amphetamines by recreational users. We report a comprehensive and detailed description of the effects of subcutaneous MDPV (1-4 mg/kg) on pharmacokinetics, biodistribution and metabolism, acute effects on thermoregulation under isolated and aggregated conditions, locomotion (open field) and sensory...
Powder Diffraction
August 22, 2017
J. Maixner, Bronislav Jurásek, Michal Himl et al.
2 citations
X-ray powder diffraction data, unit-cell parameters and space group for 2-(ethylamino)-2-(3-methoxyphenyl)cyclohexan-1-one hydrochloride, C 15 H 22 ClNO 2 , are reported [ a = 8.574(2) Å, b = 9.943(2) Å, c = 8.774(1) Å, β = 100.294(3)°, unit-cell volume V = 736(1) Å 3 , Z = 2, and space-group P 2 1 ]. All measured lines were indexed and are consistent with the P 2 1 space group. No detectable...
RSC Advances
2017
Bronislav Jurásek, Michal Himl, Radek Jurok et al.
13 citations
Methoxetamine, a designer drug marketed as a replacement for the dissociative anaesthetic ketamine, has been associated with significant numbers of hospital related intoxications and deaths in Europe.
Xenobiotica
July 12, 2016
Monika Židková, Igor Linhart, Marie Balı́ková et al.
6 citations
1. 5,6-Methylenedioxy-2-aminoindane (MDAI) is a member of aminoindane drug family with serotoninergic effect, which appeared on illicit drug market as a substitute for banned stimulating and entactogenic drugs. 2. Metabolism of MDAI, which has been hitherto unexplored, was studied in rats dosed with a subcutaneous dose of 20 mg MDAI.HCl/kg body weight. The urine of rats was collected within 24...