Behavioural, Pharmacokinetic, Metabolic, and Hyperthermic Profile of 3,4-Methylenedioxypyrovalerone (MDPV) in the Wistar Rat
Frontiers in Psychiatry April 24, 2018 Rachel R. Horsley, Eva Lhotková, Kateřina Hájková et al. 20 citations
3,4-methylenedioxypyrovalerone (MDPV) is a potent pyrovalerone cathinone that is substituted for amphetamines by recreational users. We report a comprehensive and detailed description of the effects of subcutaneous MDPV (1-4 mg/kg) on pharmacokinetics, biodistribution and metabolism, acute effects on thermoregulation under isolated and aggregated conditions, locomotion (open field) and sensory...
DOI: 10.3389/fpsyt.2018.00144 (opens in new tab)
Pharmacokinetics
Pharmacology
Thermoregulation
Cathinone
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