Journal of Psychopharmacology
December 1, 2018
Marcela Ot'Alora G, Jim Grigsby, Bruce Poulter et al.
232 citations
Posttraumatic stress disorder often does not resolve after conventional psychotherapies or pharmacotherapies. Pilot studies have reported that 3,4-methylenedioxymethamphetamine (MDMA) combined with psychotherapy reduces posttraumatic stress disorder symptoms. This pilot dose response trial assessed efficacy and safety of MDMA-assisted psychotherapy across multiple therapy teams. Twenty-eight...
Nature and Science of Sleep
November 26, 2018
Ali A El-Solh
Nightmares are considered the hallmark of posttraumatic stress disorder (PTSD). Although the characteristics of these distressing dreams may vary with the type of traumatic event, the pathophysiology exposes central dysfunction of brain structures at the level of the hippocampus, amygdala, and locus coeruleus, modulated by neurochemical imbalance in nor-adrenergic, dopaminergic, and serotonin...
Journal of Clinical Sleep Medicine
November 15, 2018
Katherine E Miller, Andrea L Jamison, Sasha Gala et al.
Study objectives: Understanding nightmares (NM) and disturbing dreams (DD) in posttraumatic stress disorder (PTSD) has been limited by the unpredictability of these events and their nonappearance in the sleep laboratory. This study used intensive, longitudinal, ambulatory methods to predict morning reports of NM/DD in veterans in whom chronic, severe PTSD was diagnosed. Methods: Participants...
Psychological Trauma: Theory, Research, Practice and Policy
November 1, 2018
Seung Suk Kang, Christopher R Erbes, Greg J Lamberty et al.
Transcendental Meditation (TM) is a mental technique using a mantra to facilitate meditation. TM has a potential for treating symptoms of posttraumatic stress disorder (PTSD), but its clinical efficacy remains to be clarified. This pilot study evaluated the acceptability, preliminary effectiveness, and neurophysiology of TM for veterans with PTSD. Twenty-nine veterans (20.7% female) were...
Journal of Traumatic Stress
October 19, 2018
Eric C Meyer, Robyn D. Walser, Barbara Hermann et al.
Posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) frequently co-occur and are associated with worse outcomes together than either disorder alone. A lack of consensus regarding recommendations for treating PTSD-AUD exists, and treatment dropout is a persistent problem. Acceptance and Commitment Therapy (ACT), a transdiagnostic, mindfulness- and acceptance-based form of behavior...
Surrey Research Insight Open Access
October 10, 2018
Michelle Ruger
This portfolio comprises a culmination of research work spanning three years of full- time training on the Practitioner Doctorate course in Psychotherapeutic and Counselling Psychology (PsychD) at the University of Surrey. The research comprises three research reports: a literature review, and two qualitative studies. The literature review explores the psychedelic renaissance, focusing on the...
Journal of Obstetric, Gynecologic, and Neonatal Nursing
October 5, 2018
Jennifer Huberty, Jeni Green, Joanne Cacciatore et al.
Objective: To explore the potential factors that mediate the relationship between mindfulness and symptoms of posttraumatic stress (PTS) in women who experienced stillbirth. Design: A cross-sectional analysis of baseline data before women's participation in an online mindfulness intervention (i.e., online yoga). Setting: This was a national study, and women participated in their own homes....
Sleep Medicine Reviews
October 1, 2018
A. Murkar, J. de Koninck
Research suggests sleep plays a role in the consolidation of recently acquired memories for long-term storage. rapid eye movement (REM) sleep has been shown to play a complex role in emotional-memory processing, and may be involved in subsequent waking-day emotional reactivity and amygdala responsivity. Interaction of the hippocampus and basolateral amygdala with the medial-prefrontal cortex is...
American Journal of Psychiatry
October 1, 2018
Jill E Bormann, Steven R Thorp, Eric Smith et al.
Previous studies suggest that group "mantram" (sacred word) repetition therapy, a non-trauma-focused complementary therapy for posttraumatic stress disorder (PTSD), may be an effective treatment for veterans. The authors compared individually delivered mantram repetition therapy and another non-trauma-focused treatment for PTSD. The study was a two-site, open-allocation, blinded-assessment...
Iranian Journal of Psychiatry and Behavioral Sciences
September 15, 2018
Abdollah Omidi, Sajedeh Hamidian
6 citations
Background: Comorbidity of anxiety and mood disorders is rather common, making the treatment of each disorder more difficult. Posttraumatic stress disorder (PTSD) is one of the anxiety disorders with a high degree of association with depression; PTSD-depression comorbidity can significantly affect the quality of life of the ones affected. Hence, using the best way to deal with each of these...