As research therapists with hundreds of hours of clinical experience supporting adults with PTSD in Phase 3 trials of MDMA assisted-therapy (MAT), we appreciate the opportunity to respond to this s...
Current research on psychedelic-assisted therapy (PAT) focuses on their potential to treat clinical psychiatric conditions such as treatment-resistant depression, anxiety, and PTSD. Presumably, if ...
Health and SocietyJanuary 8, 2025Eduardo D’avila Lins Lacerda, Bianca Medeiros Ferraz da Nóbrega, Yasmin Mesquita Dias Franca Gadelha et al.
Psychedelics have emerged as a promising approach to treating mental disorders, challenging traditional paradigms in psychiatry. This study conducted an integrative literature review to investigate the advances, challenges, and implications of the therapeutic use of these substances, addressing the guiding question: “What are the current scientific perspectives on the use of psychedelics in the...
Abstract Rationale Psychedelic-assisted therapy is increasingly applied within mental health treatment. Objectives This study focused on factors moderating changes in the acute and long-term effects of an individual psilocybin-assisted program on depression, anxiety, PTSD and personality structures by including demographic factors, subjective experience and degree of mystical type experiences...
Interest in psychedelic therapies for adults is rapidly growing, with substances like 3,4-methylenedioxymethamphetamine for posttraumatic stress disorder, psilocybin for treatment-resistant depression, and lysergic acid diethylamide for generalized anxiety disorder showing promise. However, research on these therapies in children and adolescents is limited, with no recent trials. Despite this...
According to the ICSD-3TR, nightmare disorder is characterized by extended, extremely dysphoric, and well-remembered dreams that usually involve threats to survival, security, or physical integrity. The dream experience causes clinically significant distress or impairment in social, occupational, or other important areas of functioning. Nightmare disorder occurs in 2–6% of adults. Nightmares...
Este artigo tem como objetivo realizar uma revisão bibliográfica a respeito da utilização clínica do 3,4-Metilenodioximetanfetamina (MDMA ou Ecstasy) em sessões de psicoterapia do Tratamento do Transtorno de Estresse Pós-Traumático (TEPT). Esse distúrbio é comumente tratado com antidepressivos, que atuam sobre neurotransmissores, além do acompanhamento psicoterapêutico, no entanto, alguns...
Methemoglobinemia is defined as an increase in methemoglobin of > 2% of hemoglobin. Ketamine is increasingly used for severe depression. To our knowledge, a patient with mitochondrial encephalopathy, lactic acidosis and stroke‐like episodes (MELAS) who died suddenly and unexpectedly 1–12 h after ketamine infusion with high postmortem methemoglobin has not yet been reported. The patient was a...
This paper is a systematic review of studies which aimed at improving mental health outcomes through meditation-based therapy. Specifically, this review sought to synthesize current evidences on the effect of meditation-based interventions on various mental states capable of confronting pregnant women, such as depression, anxiety, Stress, post-traumatic stress disorder (PTSD), and other mental...
This review systematically assessed the evidence on the effectiveness and safety of prāṇāyāma, traditional yogic breathing techniques, for patients diagnosed with mental disorders. We searched PubMed, PsycINFO, and Central until April 2024. We calculated standardized mean differences (SMDs) with 95% confidence intervals (CIs) from both intention-to-treat (ITT) and per-protocol (PP) data for...