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PTSD research published in 2021

Page 3 of 3: studies 41 to 58 of 58, newest first. Back to the PTSD overview

Studies

Therapeutic interventions for PTSD – current evidence on the the role of psychedelics

European Psychiatry April 1, 2021 I. Figueiredo, Filipa Viegas, F. Ferreira et al. 2 citations

Introduction Post-traumatic stress disorder (PTSD) is often a chronic condition, despite the existence of evidence-based treatment options. Psychotherapy is the designated first line treatment for PTSD, although high rates of psychiatric and medical comorbidity are observed among patients who have undergone treatment. The psychoactive properties of psychedelics may be of particular interest...

The short-term impact of 3 smoked cannabis preparations versus placebo on PTSD symptoms: A randomized cross-over clinical trial

PLoS One March 17, 2021 Marcel O Bonn-Miller, Sue Sisley, Paula Riggs et al. 129 citations

IMPORTANCE: There is a pressing need for development of novel pharmacology for the treatment of Posttraumatic Stress Disorder (PTSD). Given increasing use of medical cannabis among US military veterans to self-treat PTSD, there is strong public interest in whether cannabis may be a safe and effective treatment for PTSD. OBJECTIVE: The aim of the present study was to collect preliminary data on...

DOI: 10.1371/journal.pone.0246990 (opens in new tab) Cannabis Placebo Randomized controlled trial Pathology +1

Association of Sleep Paralysis with PTSD Symptoms, Pathological Worry and Perceived Stress

International Journal of Pulmonary & Respiratory Sciences March 8, 2021 Azal Ikhlaq

In the current study, we inspected the correlation between Sleep Paralysis and anxiety symptoms among undergraduate medical students of Pakistan. It was a questionnaire based cross-sectional study. Pre-tested, pre-designed questionnaires were administered to 100 participants and any association between sleep paralysis and PTSD symptoms, Perceived Stress, or Pathological worry was found. There...

Use of cannabinoids for the treatment of patients with post-traumatic stress disorder.

Journal of basic and clinical physiology and pharmacology March 4, 2021 Marika L Forsythe, Andrew J Boileau

Post-traumatic Stress Disorder (PTSD) is a diagnosis of extreme anxiety caused by a traumatic event. Less than 10% of individuals who have experienced severe trauma will develop this disorder. Treatment options include various psychotherapies, but not all patients respond to them. Different pharmacological approaches have been explored as potential adjuvants, including using cannabinoids to...

Stroke and Adverse Effects on The Immune and Cardiovascular Systems: The Danger of the Rise and Use of Psychedelic Drugs for Depression and PTSD

Journal of Clinical & Experimental Immunology March 3, 2021 1 citation

Depression and post-traumatic stress disorder (PTSD), in the past two decades, has been a growing problem among adults and our youth. For hundreds, if not thousands of years, plant-based psychedelic drugs, such as psilocybin and peyote, have been utilized for medical purposes by numerous native tribal people As early as 1950, lysergic acid diethylamide (LSD), a synthetic mood-altering drug, a...

Mindfulness, Posttraumatic Stress Symptoms, and Posttraumatic Growth in Aid Workers: The Role of Self-Acceptance and Rumination.

The Journal of Nervous and Mental Disease March 1, 2021 Xue Wen, Yuanyuan An, Yuyang Zhou et al.

Abstract: Objective: The risk for aid workers to develop posttraumatic mental problems highlights the importance of reducing the harm of posttraumatic stress symptoms (PTSS) and promoting the benefits of posttraumatic growth (PTG). This study examined the negative relationship between mindfulness and PTSS, and the positive relationship between mindfulness and PTG, and further explored the...

DOI: 10.1097/nmd.0000000000001275 (opens in new tab) Mindfulness Humans Occupational diseases Self concept +10

Imagery Rehearsal Based Art Therapy: Treatment of Post-traumatic Nightmares in Art Therapy.

Frontiers in Psychology January 14, 2021 Suzanne Haeyen, Merel Staal

Imagery Rehearsal Therapy (IRT) is effective for trauma-related nightmares and is also a challenge to patients in finding access to their traumatic memories, because these are saved in non-verbal, visual, or audiovisual language. Art therapy (AT) is an experiential treatment that addresses images rather than words. This study investigates the possibility of an IRT-AT combination. Systematic...

A Randomized Controlled Trial of Repeated Ketamine Administration for Chronic Posttraumatic Stress Disorder.

American Journal of Psychiatry January 5, 2021 Adriana Feder, Sara Costi, Sarah B. Rutter et al. 239 citations

OBJECTIVE Posttraumatic stress disorder (PTSD) is a chronic and disabling disorder, for which available pharmacotherapies have limited efficacy. The authors' previous proof-of-concept randomized controlled trial of single-dose intravenous ketamine infusion in individuals with PTSD showed significant and rapid PTSD symptom reduction 24 hours postinfusion. The present study is the first...

Coping With COVID-19: Mindfulness-Based Approaches for Mitigating Mental Health Crisis.

Frontiers in Psychiatry 2021 Elena Antonova, Karoly Schlosser, Rakesh Pandey et al.

The novel coronavirus disease COVID-19 that first emerged in Wuhan, China, in Nov-Dec 2019 has already impacted a significant proportion of the world population. Governments of many countries imposed quarantines and social distancing measures in 2020, many of which remain in place, to mitigate the spread of the SARS-Cov-2 virus causing the COVID-19 disease. The direct impact of COVID-19 on...

Treatment of PTSD with MDMA as a method of counteracting the incidence of suicide. A discussion in the context of Polish law

Acta Iuris Stetinensis 2021 Konrad Burdziak

Przedmiotem pracy uczyniono problematykę leczenia PTSD z wykorzystaniem MDMA jako sposobu przeciwdziałania zjawisku samobójstwa. Rozważania w tym zakresie przeprowadzono na tle polskiego prawa. W pracy wykorzystano metodę dogmatycznoprawną. Zdecydowano się przy tym skorzystać z derywacyjnej koncepcji wykładni prawa autorstwa M. Zielińskiego. Autor pracy ustalił, że: 1) PTSD może stanowić źródło...

Self-reported PTSD is associated with increased use of MDMA in adolescents with substance use disorders

European Journal of Psychotraumatology 2021 Lukas A Basedow, Sören Kuitunen-Paul, Melina Wiedmann et al. 15 citations

ABSTRACT Background: Adolescent patients with a substance use disorder (SUD) often fulfil the criteria for a co-occurring post-traumatic stress disorder (PTSD). However, it is not clear if these dual-diagnosed adolescents present with unique levels of substance use and how their substance use relates to PTSD symptom clusters. Objective: To investigate substance use in adolescents with...

Using Drugs to Treat Drug Dependence: Exploring the Use of MDMA-Assisted Psychotherapy for Individuals with PTSD and Concurrent Substance Use

Psychology and Behavioral Sciences 2021 Brenda Tichler

The importance of treating concurrent Post-Traumatic Stress Disorder (PTSD) and substance use with psychedelics is a controversial topic, hampered in part by a lack of empirical evidence and rigidity of substance scheduling. Traditional treatments for concurrent PTSD and substance use concerns are compartmentalized, with clinicians focusing on one condition over the other. In addition,...

3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for victims of sexual abuse with severe post-traumatic stress disorder: an open label pilot study in Brazil.

Revista Brasileira de Psiquiatria 2021 Alvaro V Jardim, Dora V Jardim, Bruno Rasmussen Chaves et al. 54 citations

To conduct Brazil's first clinical trial employing 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for post-traumatic stress disorder (PTSD), given its high prevalence resulting from epidemic violence. Of 60 volunteers, four matched the inclusion & exclusion criteria. Three patients with PTSD secondary to sexual abuse (diagnosed by the Structured Clinical Interview for DSM-IV...

The potential use of N-methyl-3,4-methylenedioxyamphetamine (MDMA) assisted psychotherapy in the treatment of eating disorders comorbid with PTSD.

Medical Hypotheses 2021 Timothy D Brewerton, Adele Lafrance, Michael C Mithoefer 28 citations

Despite advances in the field, eating disorders (EDs) remain very challenging disorders to treat, especially when comorbid with posttraumatic stress disorder (PTSD). N-methyl-3,4-methylenedioxyamphetamine (MDMA)-assisted psychotherapy for treatment refractory PTSD shows great promise, with two-thirds of participants achieving full remission at 1 year or more at follow-up. PTSD is a common...

DOI: 10.1016/j.mehy.2020.110367 (opens in new tab) Full text (opens in new tab) PTSD Eating disorders MDMA-Assisted Psychotherapy Posttraumatic stress disorder +6

Relational and Growth Outcomes Following Couples Therapy With MDMA for PTSD.

Frontiers in Psychiatry 2021 Anne C Wagner, Rachel E Liebman, Ann T Mithoefer et al. 40 citations

Healing from trauma occurs in a relational context, and the impacts of traumatic experiences that result in post-traumatic stress disorder (PTSD) go beyond the diagnosis itself. To fully understand a treatment for PTSD, understanding its impact on interpersonal, relational, and growth outcomes yields a more fulsome picture of the effects of the treatment. The current paper examines these...

DOI: 10.3389/fpsyt.2021.702838 (opens in new tab) Full text (opens in new tab) Interpersonal functioning Post-traumatic growth MDMA Therapy: MDMA MDMA-Assisted Therapy +13

Case Report: Why Sleep and Dream Related Psychological Treatments, Such as Sleepcoaching (According to Holzinger&Klösch) and CBT-I Should Be Implemented in Treatment Concepts in the Public Health System-Description of the Nightmare Treatment Process in the Context of PTSD.

Frontiers in Psychology 2021 Brigitte Holzinger, Franziska Nierwetberg, Gerhard Klösch 2 citations

In this case report, we explain the story of a woman diagnosed with severe PTSD, suffering from recurrent nightmares involving a traumatizing event. She participated in 6 week lucid dreaming training to help her reduce her nightmare frequency. Our descriptions include her dream reports as well as the results of the psychological assessment conducted. In only 6 weeks, she was able to begin to...