June 16, 2025
Bruno Ramos Gomes, Bruno Rasmussen Chaves
Ibogaine, derived from the Iboga (Tabernanthe iboga), a shrub of central Africa, has a history of medical and entheogenic ritual use. Its modern use followed the serendipitous discovery, among heroin users in 1962, that it interrupted heroin addiction. Efforts to engage the scientific community in the clinical science of ibogaine had limited success but led to an underground treatment movement...
Research Square
September 8, 2022
Maria Helha Fernandes-Nascimento, André Brooking Negrão, Karine Viana-Ferreira et al.
Abstract Objective To evaluate the publications on ibogaine use for substance-related disorders treatment over the last three decades. Method Bibliometric analysis of publications on ibogaine for the treatment of substance-related disorders from 1991 to 2020 using VOSviewer software. We performed a Scopus database search using the terms: ibogaine, 12-methoxybogamine, endabuse, tabernanthe...
Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
2021
Alvaro V Jardim, Dora V Jardim, Bruno Rasmussen Chaves et al.
54 citations
To conduct Brazil's first clinical trial employing 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for post-traumatic stress disorder (PTSD), given its high prevalence resulting from epidemic violence. Of 60 volunteers, four matched the inclusion & exclusion criteria. Three patients with PTSD secondary to sexual abuse (diagnosed by the Structured Clinical Interview for DSM-IV...
Journal of psychopharmacology (Oxford, England)
November 1, 2014
Eduardo Ekman Schenberg, Maria Angélica de Castro Comis, Bruno Rasmussen Chaves et al.
110 citations
Ibogaine is an alkaloid purported to be an effective drug dependence treatment. However, its efficacy has been hard to evaluate, partly because it is illegal in some countries. In such places, treatments are conducted in underground settings where fatalities have occurred. In Brazil ibogaine is unregulated and a combined approach of psychotherapy and ibogaine is being practiced to treat...