Life
November 8, 2023
Bruno Pires, Luana M. Rosendo, Ana Teresa Brinca et al.
15 citations
This review delves into the therapeutic applications of amphetamine-type stimulants such as lisdexamphetamine dimesylate, mixed amphetamine salts, 3,4-methylenedioxymethamphetamine (MDMA), dextroamphetamine, and phentermine. These compounds have been investigated for their potential in treating a range of psychiatric disorders, including attention deficit hyperactivity disorder (ADHD), drug...
JAPhA Practice Innovations
November 8, 2023
Elizabeth Sugiarto, Rebecca Leung, Jamie Yuen
1 citation
AbstractBackground Psilocybin is the main psychoactive component of a naturally occurring psychedelic organism commonly referred to as "magic mushrooms." Existing literature demonstrates beneficial neurologic effects in treatment-resistant depression, cancer-associated depression and anxiety, and substance use. The evidence base for psilocybin use is on the rise with the U.S. Food and Drug...
Pharmacological Reports
November 6, 2023
Paweł Holas, Justyna Kamińska
39 citations
Abstract There has been increasing scientific and clinical interest in studying psychedelic and meditation-based interventions in recent years, both in the context of improving mental health and as tools for understanding the mind. Several authors suggest neurophysiological and phenomenological parallels and overlaps between psychedelic and meditative states and suggest synergistic effects of...
Neuroethics
November 6, 2023
Edward Jacobs, Ashleigh Murphy-Beiner, Ian Rouiller et al.
23 citations
Abstract The ethical value—and to some scholars, necessity—of providing trial patients with post-trial access (PTA) to an investigational drug has been subject to significant attention in the field of research ethics. Although no consensus has emerged, it seems clear that, in some trial contexts, various factors make PTA particularly appropriate. We outline the atypical aspects of psychedelic...
RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218
November 5, 2023
Sara Almeida Oliveira, Victor Augusto Rodovalho Fava
A psilocibina é o princípio ativo dos cogumelos da espécie Psilocybe cubensis, historicamente conhecidos como cogumelos mágicos. É um agonista dos receptores serotoninérgicos 5HT2A. O seu uso para o tratamento do transtorno de ansiedade generalizada e da depressão em indivíduos com câncer em estágio terminal apresenta resultados promissores em ensaios clínicos. Objetivo: Revisão da literatura...
Diseases
November 3, 2023
Kainat Riaz, Sejal Suneel, Mohammad Hamza Bin Abdul Malik et al.
16 citations
Post-traumatic stress disorder (PTSD) is a debilitating mental health disorder that causes significant dysfunction in individuals. Currently, there are many approved pharmacotherapy and psychotherapy treatment options for PTSD, but unfortunately, half of the patients do not respond to traditional therapies. In this article, we review clinical trials and research on...
Journal of Psychoactive Drugs
November 3, 2023
Marija Franka Žuljević, Antonija Mijatović, Stjepan Ljudevit Marušić et al.
6 citations
Analyzing online retrospective experience reports of psychedelic use can provide valuable insight into their acute subjective effects. Such reports are unexplored in relation to mystical states, which are thought to be a therapeutic mechanism within psychedelic-assisted psychotherapy. We created a set of words that, when encountered in an experience report, indicate the occurrence of mystical...
Psychoanalytic Dialogues
November 2, 2023
Noelle Burton
ABSTRACT This is a reply to the discussions by Arthur Fox, Megan Rundel, and Jeffrey Guss. Clarification is made on the utility of diagnosis, as well as further elaboration on what is common to both psychedelic states and the altered states of consciousness encountered in deep psychoanalytic work. Additional thoughts on the integration of a relational multiple self-state model with psychedelic...
The American Journal of Drug and Alcohol Abuse
November 2, 2023
Fernando Mendive, Cecile Giovannetti, Sara García Arce
4 citations
Background: There exists an underexploited opportunity to develop innovative therapeutic approaches to SUDs based upon the complementarity between modern and traditional health systems.Objectives: Illustrate the feasibility and potentiality of such an approach through the comprehensive description of Takiwasi Center's treatment model and program, where health concepts and practices from...
bioRxiv (Cold Spring Harbor Laboratory)
November 2, 2023
Jordan Taylor Jacobs, Alan Rockefeller, Harte Singer et al.
4 citations
preprint
Abstract Psilocybe zapotecorum is a strongly blue-bruising psilocybin mushroom used by indigenous groups in southeastern Mexico and beyond. While this species has a rich history of ceremonial use, research into its chemistry and genetics have been limited. Herein, we detail mushroom morphology and report on cultivation parameters, chemical profile, and the full genome sequence of P. zapotecorum...