Open Mind
2026
Alexi Mary Theofanous
preprint
Recent research into psychedelic-assisted psychotherapy has largely emphasised pharmacological mechanism such as neuroplasticity and symptom reduction, with less attention to the relational processes through which therapeutic change is supported and integrated. Given that such experiences are central to therapeutic change, this introduces a significant limitation: variability in therapist...
Open Mind
2026
Amin Nazmuddin Mohammadi, Christine Wekerle
preprint
Alcohol use disorder (AUD) is a prevalent and chronic psychiatric condition characterized by impaired control over alcohol use, compulsive consumption, and high rates of relapse (Grant et al., 2015; Kurihara, 2023). Despite the availability of pharmacological and psychosocial interventions, treatment outcomes remain suboptimal, with substantial rates of non-response and relapse (Lohoff, 2022;...
Open Mind
2026
Katarzyna Korsak, Daniel Pankowski, Paweł Holas
preprint
The clinical use of psychedelic substances and Psychedelic-Assisted Therapy (PAT) is an area of growing interest that also raises significant social concerns and controversy. Despite existing legal restrictions, empirical research on substances such as psilocybin, mescaline, MDMA, LSD, DMT, and ibogaine has been developing, particularly in the treatment of conditions such as treatment-resistant...
Journal of Music Therapy
2026
Clare O’callaghan, Voula Kallianis, Margaret Ross
Limited evidence supports treatment for distress in life-threatening illness. Psychedelic-assisted psychotherapy (PAP) may help. Despite music's presence in PAP, sparse accounts of music-related experiences exist. Such research is needed to optimize music's presence within PAP. This qualitative analysis aimed to understand participants' music-related accounts of their PAP experiences within a...
General Hospital Psychiatry
2026
Martin L Williams, Karen Hitchcock, Angus H Miller et al.
Clinical research in psychedelic-assisted therapies is flourishing following the resumption of human trials exploring classic psychedelics and their therapeutic application to a range of mental health conditions. Translation from research to the clinic is underway in Australia and appears imminent in several other countries. Classic psychedelics function primarily as agonists of a subgroup of...
Issues in Mental Health Nursing
2026
Jennifer Tustison, Charlene Niemi, Kristen R. Choi
1 citation
The integration of psychedelic substances into mental health treatments represents one of the most significant paradigm shifts in psychiatric care in recent decades. This article examines the ethic...
PLoS One
2026
Diego Castellano-Ramírez, Elisa Hernández-Álvarez, Lucas F Borkel et al.
Psychedelic-assisted therapy is regaining attention as a promising approach to treating mental health disorders. This research aimed to compare related factors regarding the therapeutic use of psychedelics between medical and nursing students, addressing a notable gap in existing research. A cross-sectional survey was conducted at the University of Las Palmas de Gran Canaria (Spain) during the...
Case Reports in Psychiatry
2026
Ridhi J. Vyas, Ryan Hood, Jeremy Hsiang et al.
3,4‐Methylenedioxymethamphetamine (MDMA)‐assisted psychotherapy (MDMA‐AP) has shown promise in treating post‐traumatic stress disorder (PTSD), particularly in treatment‐resistant cases. However, little is known about its potential to precipitate adverse psychiatric outcomes. We present the case of a 31‐year‐old woman with nondistressing childhood compulsions, chronic PTSD, and complex medical...
Therapeutic Advances in Psychopharmacology
2026
Kristian Beichmann, Polina Catzeflis, Helena Aicher et al.
The Swiss Federal Office of Public Health provides case-by-case exemptions allowing physicians to provide psychedelic-assisted therapy (PAT) using psilocybin, lysergic acid diethylamide (LSD), or 3,4-methylenedioxy-N-methamphetamine (MDMA). The study provided an overview of PAT as currently provided in Switzerland under the regulatory framework of the Federal Office of Public Health (FOPH)....
Medicinska istrazivanja
2026
Stefan Jerotić, Olga Čolović, Nađa Marić
Psychedelic-assisted psychotherapy (PAP) is emerging as a novel intervention for major psychiatric disorders, most notably major depressive disorder (MDD) and post-traumatic stress disorder (PTSD). While psychotherapy is widely regarded as a core element of PAP its precise role remains poorly defined. This narrative review traces the development of PAP within contemporary Western psychiatry,...