Neuroplasticity: all studies (page 20) - The Consciousness Library

Effects of psilocybin on hippocampal neurogenesis and extinction of trace fear conditioning

Experimental Brain Research June 1, 2013 Briony J. Catlow, Shijie Song, Daniel Paredes et al. 266 citations

Drugs that modulate serotonin (5-HT) synaptic concentrations impact neurogenesis and hippocampal (HPC)-dependent learning. The primary objective is to determine the extent to which psilocybin (PSOP) modulates neurogenesis and thereby affects acquisition and extinction of HPC-dependent trace fear conditioning. PSOP, the 5-HT2A agonist 25I-NBMeO and the 5-HT2A/C antagonist ketanserin were...

DOI: 10.1007/s00221-013-3579-0 Neurogenesis Fear conditioning Dentate gyrus Hippocampal formation +4

Neuroplasticity and the next wave of antidepressant strategies

Frontiers in Cellular Neuroscience 2013 Shawn P. Hayley, Darcy Litteljohn 92 citations

Depression is a common chronic psychiatric disorder that is also often co-morbid with numerous neurological and immune diseases. Accumulating evidence indicates that disturbances of neuroplasticity occur with depression, including reductions of hippocampal neurogenesis and cortical synaptogenesis. Improper trophic support stemming from stressor-induced reductions of growth factors, most notably...

DOI: 10.3389/fncel.2013.00218

Functional diversity on synaptic plasticity mediated by endocannabinoids.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences December 5, 2012 Roger Cachope

Endocannabinoids (eCBs) act as modulators of synaptic transmission through activation of a number of receptors, including, but not limited to, cannabinoid receptor 1 (CB1). eCBs share CB1 receptors as a common target with Δ(9)-tetrahydrocannabinol (THC), the main psychoactive ingredient in marijuana. Although THC has been used for recreational and medicinal purposes for thousands of years,...

DOI: 10.1098/rstb.2011.0386 Full text

Cognitive-Affective Neural Plasticity following Active-Controlled Mindfulness Intervention

Journal of Neuroscience October 31, 2012 Micah Allen, Martin Dietz, Karina S. Blair et al. 389 citations

Mindfulness meditation is a set of attention-based, regulatory, and self-inquiry training regimes. Although the impact of mindfulness training (MT) on self-regulation is well established, the neural mechanisms supporting such plasticity are poorly understood. MT is thought to act through interoceptive salience and attentional control mechanisms, but until now conflicting evidence from...

DOI: 10.1523/jneurosci.2957-12.2012 Mindfulness Neuroplasticity Anterior cingulate cortex Stroop effect +9

Modeling Ketamine Effects on Synaptic Plasticity During the Mismatch Negativity

Cerebral Cortex August 8, 2012 André Schmidt, Andreea O. Diaconescu, Michael Kometer et al. 110 citations

This paper presents a model-based investigation of mechanisms underlying the reduction of mismatch negativity (MMN) amplitudes under the NMDA-receptor antagonist ketamine. We applied dynamic causal modeling and Bayesian model selection to data from a recent ketamine study of the roving MMN paradigm, using a cross-over, double-blind, placebo-controlled design. Our modeling was guided by a...

DOI: 10.1093/cercor/bhs238 Full text Synaptic plasticity Ketamine Neuroplasticity Mismatch negativity +2

What does Neural Plasticity Tell us about Role of Primary Visual Cortex (V1) in Visual Awareness?

Frontiers in Psychology January 20, 2011 Juha Silvanto, Geraint Rees

The complete loss of visual awareness resulting from a lesion to the primary visual cortex (V1) suggests that this region is indispensable for conscious visual perception. There are however a number cases of conscious perception in the absence of V1 which appear to challenge this conclusion. These include reports of patients with bilateral V1 lesions sustained at an early age whose conscious...

DOI: 10.3389/fpsyg.2011.00006 Full text Plasticity Transcranial magnetic stimulation Consciousness Blindsight +3

Zen and Neural Plasticity without Training or Stimulation: ''Be Aware!''

Frontiers in Computational Neuroscience 2011 Dinse Hubert

As a consequence, changes in the external world alter brain organization, which lead to changes in perception and behaviour. However, little is known [2,3] how purely internal, mental states – such as the focus of attention, imagery or meditation – affect behaviour and performance in the absence of external stimulation. The effects of altered external stimulation of the body on somatosensory...

DOI: 10.3389/conf.fncom.2011.53.00097