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Microdosing: all studies

Page 44 of 56: studies 431 to 440 of 555, newest first. Back to the microdosing overview

Research

Repeated low doses of psilocybin reduces perceived symptom severity of obsessive-compulsive disorder, but fails to restore cognitive flexibility: A case study of identical twins

December 30, 2024 Sivert Drange, Jacob Cohen, Sys Stybe Johansen et al. 1 citation preprint

Background: Obsessive-Compulsive Disorder (OCD) presents significant challenges to individuals mental health, characterized by intrusive thoughts and repetitive maladaptive behaviours. Recent exploration into alternative treatments has spotlighted psychedelics, notably psilocybin, for their potential therapeutic benefits in different psychiatric disorders, including OCD. This case study delves...

DOI: 10.31219/osf.io/2bxe8 (opens in new tab) Psilocybin Obsessive compulsive Cognitive flexibility Flexibility engineering +3

Reading the crowd: attitudes toward psychedelics and psychedelic therapies among attendees at a conference

Psychedelics December 17, 2024 Zachary Bosshardt, Jessica L Maples-Keller, Deanna M Kaplan et al.

Social attitudes, policy, and perceptions of psychedelics are currently undergoing considerable change. Growing public salience of psychedelics has been accompanied by the emergence of conferences focused on psychedelic education and dialogue. Attendees at such events compose an important group of stakeholders in psychedelic science and practice; their views of psychedelics can be valuable for...

DOI: 10.61373/pp024r.0040 (opens in new tab) Reading process Linguistics

Psilocybin causes sex, time, and dose dependent alterations in brain signaling pathways

bioRxiv (Cold Spring Harbor Laboratory) December 17, 2024 J. Hudson Barnett, Kennedi T. Todd, Joseph Benetatos et al. 1 citation preprint

Abstract Psilocybin is a psychedelic tryptamine that has emerged as a potential candidate for the treatment of a variety of conditions, including treatment resistant depression and post-traumatic stress disorder. Clinical trials which have assessed the efficacy of psilocybin for these conditions report a rapid and sustained improvement in patient- and clinician-rated depression scores. The...

The many faces of psilocybin-related psychosis: A case series

Psychiatry Research Case Reports December 7, 2024 Yumin Kim, Rachel Bigley, Aubrey DeVinney et al. 4 citations

Psilocybin use has been increasingly popular in the United States, and its use as a novel therapeutic treatment for psychiatric conditions has led to greater public acceptance as a recreational substance. Consequently, clinicians are faced with managing complications and adverse effects associated with psilocybin use. We present three cases seen in a dual diagnosis inpatient psychiatry unit...

LSD: DE DROGA PSICODÉLICA A POSSÍVEL ALIADA NO TRATAMENTO DE DISTÚRBIOS PSICOLÓGICOS

Revista Ibero-Americana de Humanidades, Ciências e Educação December 4, 2024 Tamyres Cordeiro Leoncio, Danilo Cândido de Araújo Batista

O LSD (dietilamida do ácido lisérgico), tradicionalmente conhecido por seus efeitos psicodélicos, tem atraído crescente interesse na pesquisa científica devido ao seu potencial terapêutico em uma série de distúrbios neurológicos e psiquiátricos. Este artigo revisa as evidências recentes sobre os efeitos do LSD, destacando sua capacidade de promover a neuroplasticidade, modular o sistema...

Single-dose 1cp-LSD administration for canine anxiety: a pilot study.

Veterinary research communications December 1, 2024 Luis Alberto Henríquez-Hernández, Ignacio García-Serrano, Domingo J Quintana-Hernández et al. 4 citations

Anxiety affects 14-20% of dogs. Pharmacological treatments often fail. Psychedelics have shown to be useful for anxiety and depression in humans, but their veterinary use remains unexplored. We aimed to determine the effects of low-dose 1-cyclopropionyl-d-lysergic acid diethylamide (1cp-LSD) administered in a single dose to a dog, to observe the effect and establish the safety of the substance....

Will Psychedelics Propel Your Career? Exploring the Potential Impact of Psychedelics on Work, Productivity and Well-Being

Human Capital Leadership Review November 1, 2024 Jonathan Westover

With growing research demonstrating the therapeutic potential of psychedelics such as psilocybin and MDMA in treating mental health conditions, interest is mounting around potential applications beyond health. This article explores emerging evidence on the impact of psychedelics in key domains relevant to careers and the workplace including creativity, focus, stress and burnout, leadership,...

Psilocybin-assisted neurofeedback for the improvement of executive functions: a randomized semi-naturalistic-lab feasibility study

Philosophical transactions of the Royal Society of London. Series B, Biological sciences October 21, 2024 Stefanie Enriquez‐geppert, Jaroslav Krc, Fiachra O'Higgins et al. 5 citations

Executive function deficits, common in psychiatric disorders, hinder daily activities and may be linked to diminished neural plasticity, affecting treatment and training responsiveness. In this pioneering study, we evaluated the feasibility and preliminary efficacy of psilocybin-assisted frontal-midline theta neurofeedback (NF), a neuromodulation technique leveraging neuroplasticity, to improve...

Expanding the Therapeutic Horizons of Psilocybin in Mental Health

ACS Medicinal Chemistry Letters October 15, 2024 Robert B. Kargbo 1 citation

Psilocybin, a naturally occurring psychedelic compound, has recently emerged as a promising therapeutic agent for mental health. This Patent Highlight explores the innovative approaches to harnessing psilocybin's potential across various contexts. These include clinical trials targeting severe psychiatric conditions, the integration of low-dose psilocybin into dietary products to promote...

DOI: 10.1021/acsmedchemlett.4c00488 (opens in new tab) Psilocybin New horizons Hallucinogen Mental health +1

Qualitative Research on Psilocybin-Assisted Psychotherapy for the Treatment of Mental Health Disorders: A Scoping Review Protocol

October 7, 2024 Jennifer Pincombe, M.l. Williams, Sean Carruthers et al. 1 citation preprint

IntroductionThere has been a surge in research into psilocybin-assisted psychotherapy over the past decade, with many studies indicating this may be an effective novel intervention for several mental health disorders. Researchers are increasingly incorporating qualitative analysis into their studies in recognition of the rich, contextual information this provides. This scoping review aims to...

DOI: 10.31234/osf.io/ga9p2 (opens in new tab) Psilocybin Psychotherapist Mental health Protocol science +5