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MDMA: all studies

Page 243 of 346: studies 2,421 to 2,430 of 3,454, newest first. Back to the MDMA overview

Research

Personal experience and theology: St. Symeon the New Theologian

Zenodo (CERN European Organization for Nuclear Research) November 1, 2026 Marius Popescu preprint

The theological work of St. Symeon the New Theologian, long marginalized by ”official” academic theology and preserved mainly within monastic circles, has in recent decades become the subject of growing scholarly interest. This article examines the originality of St. Symeon’s theology—rooted firmly in Scripture and Patristic Tradition, yet distinguished by the central place it gives to the...

A Comparative Study of Spiritual Imagination in W. B. Yeats and Sri Aurobindo's Poetry

Zenodo (CERN European Organization for Nuclear Research) October 31, 2026 Shailesh Tukaram Bagdane preprint

Abstract: Yeats's theosophical efforts awakened him to supernatural entities and soul elements of the universe especially in Irish tradition and mythology. Yeats developed visions of another world and aspired to metaphysically achieve spiritual and universal significance. Yeats concretely located the everlasting philosophies in spiritual and universal significance. In the process Yeats’s poetry...

Volumetric dilution nasal spray as a harm reduction strategy for intranasal psychoactive substance use: a practical framework and rationale

Harm Reduction Journal October 30, 2026 Alexandre Delforge

Abstract: Background: Intranasal insufflation of psychoactive substances, including cocaine, MDMA, and ketamine, is associated with a well-documented spectrum of nasal and sinonasal complications. These result from at least three distinct but interacting mechanisms: mechanical trauma from particulate matter, vasoconstriction-induced mucosal ischaemia (primarily relevant for cocaine), and...

DROGAS ILÍCITAS COM ALTO POTENCIAL DE NEUROTOXICIDADE: UMA REVISÃO DE ESCOPO

Artefactum October 28, 2026 Pablo Henrique Ramos Silva, Julyana Padilha Sousa, Maria Gabrielly Ferreira Silva et al.

Mapear os mecanismos de neurotoxicidade associados a drogas ilícitas selecionadas, seus efeitos relatados sobre o sistema nervoso central e potenciais estratégias neuroprotetoras. Métodos: Revisão de escopo baseada em busca no PubMed, abrangendo publicações de 2020 a 2025, em português, inglês ou espanhol, com texto completo gratuito. O registro de seleção apresentado no trabalho identificou...

Psychedelic assisted psychotherapy (2020–2025): a scoping review of clinical evidence, mechanisms, safety, and ethics

Frontiers in Psychology October 27, 2026 Nasiru Mohammed Abdullahi, Rashid Menhas, Patience Osose Nasir et al.

Background: Clinical research on psychedelic-assisted therapy (PAT) has expanded substantially in recent years, particularly for post-traumatic stress disorder (PTSD) and depressive disorders. Contemporary studies have generally evaluated psychedelic administration within controlled therapeutic settings that include psychological support, preparation, and integration. However, variability in...

Perceived versus Target-Scored Empathic Accuracy under Psychedelics: A Measurement Gap and a Proposed Test

Zenodo (CERN European Organization for Nuclear Research) October 26, 2026 Vasileios Sampalis preprint

Psychedelics are increasingly described as deepening empathy and understanding of others, a claim drawn from increases in emotional empathy and self-reported connectedness. These measures index how people feel. None establishes whether the inferences people draw about others are accurate. Empathic accuracy (EA) is accurately inferring the specific content of another's thoughts and feelings,...

TERAPIAS ASSISTIDAS POR PSICODÉLICOS EM PSIQUIATRIA: EVIDÊNCIAS CLÍNICAS, MECANISMOS NEUROBIOLÓGICOS E DESAFIOS REGULATÓRIOS

Zenodo (CERN European Organization for Nuclear Research) October 20, 2026 Lara Vervloet Carvalho, Sarah Isabela Magalhães Costa, Nathália Marques Santos et al. preprint

As terapias assistidas por psicodélicos emergiram, na última década, como estratégia de investigação de destaque para transtornos psiquiátricos refratários às abordagens convencionais. Em ensaio de fase 2 controlado, dose única de 25 mg de psilocibina produziu redução média de 12,0 pontos na escala MADRS em pacientes com depressão resistente ao tratamento, superior à condição controle de 1 mg....

Adverse outcomes of psychedelics self‐reported: Survey

Alcoholism & Drug Abuse Weekly October 16, 2026 Alison Knopf

A nationally representative cross‐sectional survey of U.S. adults found the among all psychedelics, ibogaine and 5‐MeO‐DMT (5‐methoxy‐N,N‐ dimethyltryptamine) resulted in the most frequent self‐reported adverse outcomes, according to a recent study. The study, “Adverse Health Outcomes of Psilocybin, LSD, MDMA, Ibogaine, and 5‐MeO‐DMT,” by Otto Simonsson, Ph.D., and colleagues, was published...

AI-assisted characterization of psychedelic clinical trials from ClinicalTrials.gov

Trials October 14, 2026 Luca Pani, Fabio Tascedda

Abstract: Background: The registry record of psychedelic and related rapid-acting compounds is large, heterogeneous and laborious to synthesize by hand. We tested whether a large language model (LLM) with live access to the ClinicalTrials.gov application programming interface (API) could produce a timely, structured and reproducible characterization of this landscape. Methods: Cross-sectional...

Pharmacokinetic disposition in oral fluid, excretion profile, and subjective and physiological responses following oral and intranasal administration of Clophedrone (3-CMC)

October 13, 2026 Nunzia La Maida, Lourdes Poyatos, Annagiulia Di Trana et al.

Background and Purpose: Clophedrone (3-chloromethcathinone, 3-CMC) belongs to the methcathinone subclass of ring-substituted cathinones, a prominent group of new psychoactive substances (NPS) present in the illicit drug market. To date no studies have assessed concentrations and acute effects of 3-CMC in humans after self-administration. Experimental Approach: A total of 16 psychostimulant...