Pharmacotherapy in Psychiatry and Neurology
2020
Kamil Kozera, Lena Cichoń, Krzysztof M. Wilczyński et al.
MDMA (3,4-methylenedioxymethamphetamine) is a psychoactive substance classified as a hallucinogen. MDMA acts in the brain through a variety of neurochemical mechanisms, reducing anxiety, giving a sense of oneness with other people, expanding empathy, sharpening the senses and intensifying the experience of emotions. Therefore, the use of the MDMA assisted psychotherapy is being considered in...
Basic and clinical neuroscience
2020
Nor Suliana Mustafa, Nor Hidayah Abu Bakar, Nasir Mohamad et al.
N-Methyl-3, 4-methylenedioxyamphetamine (MDMA), or ecstasy is a recreational drug of abuse. It is a synthetic substance that affects the body's systems, which its mechanism of action and treatment should be more investigated. MDMA provides an immediate enjoyable feeling by stimulating the release of neurotransmitters, such as dopamine and serotonin in the brain. Unfortunately, abnormal...
edoc (University of Basel)
2020
Patrick Vizeli
Psychoactive substances such as the ring substituted phenylethylamine 3,4-methylenedioxymethamphetamine (MDMA; “ecstasy”) are widely used in recreational settings. Additionally, recent research highlights substance-assisted psychotherapy as potential new effective treatment for various psychiatric disorders, e.g. post-traumatic stress disorder (PTSD). MDMA releases and inhibits the uptake of...
Progress in Neuro-Psychopharmacology and Biological Psychiatry
2020
Anees Bahji, Ashleigh Forsyth, D. Groll et al.
85 citations
BACKGROUND Posttraumatic stress disorder (PTSD) is a common psychiatric condition that can develop following a traumatic experience. PTSD is associated with significant disability, a large economic burden, and despite the range of therapies to treat PTSD, response to antidepressants is limited. A growing body of clinical research suggests the efficacy of 3,4-methylenedioxymethamphetamine...
European Addiction Research
2020
Franz Moggi, Deborah Schorno, Leila M. Soravia et al.
22 citations
<b><i>Background:</i></b> Attention deficit/hyperactivity disorder (ADHD), conduct disorder (CD), and sensation seeking (SS) have been consistently related to a higher risk of substance use (SU) and substance use disorder (SUD). <b><i>Objectives:</i></b> To investigate the relationship between ADHD and prevalence rates in males at age 20 and age 25, the initiation of SU and SUD after age 20,...
Drug Science, Policy and Law
2020
Natasha L. Mason, Patrick C. Dolder, Kim P. C. Kuypers
15 citations
Background It has been suggested that the outcome of the psychedelic experience is dependent on set and setting. While scientific research into the therapeutic potential of psychedelics is growing, it is clear that in clinical populations an optimal set and setting will not always be attainable. It was aimed to assess under which emotional and environmental circumstances psychedelic users use...