bioRxiv Preprint Server
June 16, 2025
Nor Suliana Mustafa, Nasir Mohamad, Nor Hidayah Abu Bakar et al.
preprint
MDMA induced the activation of microglia in the brain which would lead to neurotoxicity. The activation of microglia is associated with morphological changes and the production of inflammatory phenotypes. While there is research suggesting that thymoquinone (TQ) may have anti-inflammatory effects and modulate microglial activation, studies specifically focusing on its impact on activated...
ASM Science Journal
November 17, 2023
Nor Suliana Mustafa, Mohd Nazri Mohd Daud, Nor Hidayah Abu Bakar et al.
MDMA (3, 4 Methylenedioxymethamphetamine) is a psychoactive drug under the amphetamine-type stimulant group. While the modulatory effects of MDMA on serotonin neurotransmission and its neurotoxicity in the central nervous system are well studied, MDMA’s effects on modulating microglial neuroimmune functions have attracted considerable attention. Resident glial cells, including microglia in the...
Venoms and Toxins
September 15, 2023
Nor Suliana Mustafa, Mohd Nazri Mohd Daud, Nasir Mohamad et al.
Keywords: 3, 4 methylenedioxymethamphetamine, MDMA, microglia, neurotoxicity syndrome, inflammation, phenotype.
Basic and clinical neuroscience
2020
Nor Suliana Mustafa, Nor Hidayah Abu Bakar, Nasir Mohamad et al.
N-Methyl-3, 4-methylenedioxyamphetamine (MDMA), or ecstasy is a recreational drug of abuse. It is a synthetic substance that affects the body's systems, which its mechanism of action and treatment should be more investigated. MDMA provides an immediate enjoyable feeling by stimulating the release of neurotransmitters, such as dopamine and serotonin in the brain. Unfortunately, abnormal...