Abstract Initial interest in the value of psychedelic drugs (“psychotomimetics”) in psychiatry began in the early 20th century, with explorations of the possibility that mescaline or peyote could produce psychosis-like effects. Over time, interest was focused on whether the effects of psychedelics could inform as to the underlying basis for psychiatric disorders. As research continued, and...
December 1, 2020Caroline Mathon, Christèle Widmer, R. Mégevand et al.
Objectif Depuis de nombreuses annees, la politique en matiere de drogues est basee en Suisse sur quatre piliers, a savoir la prevention, la therapie, la repression et la reduction des risques. Parmi les actions mises en œuvre concernant la reduction des risques lies aux consommations recreatives de substances psychoactives, une nouvelle offre a ete proposee depuis 2019 a Geneve, consistant en...
ABSTRACT Over the last three decades, the renaissance of interdisciplinary research into psychedelic drugs has challenged the Cartesian notions of subjectivity and identity that have endured throughout modernity. But as work in this field reaches new degrees of complexity, the limitations of verbal and textual language are presenting barriers to conventional forms of scholarship. Across the...
This case report describes a 39-year-old male with remote history of polysubstance use disorder and depression who developed tinnitus after use of inhaled N,N-dimethyltryptamine (DMT). Although development of ear ringing was attributed to use on a single occasion, tinnitus occurred within the context of a larger self-experiment involving weekly microdoses of lysergic acid diethylamide (LSD)....
Mahler, who had mobilized the youth of his day against slovenly Tradition, reerupted into a newly youthful popular culture in the 1960s thanks to both the centenary of his birth and the advent of the long-playing record. Not only musicians were touched by the wave of new recordings; modern pop culture and youthful “avant-garde” now blithely bridged the once-opposed realms of “high” and “low”...
Despite a politically vilified past, classical psychedelics, including lysergic acid diethylamide (LSD), psilocybin, and dimethyltryptamine (DMT), are experiencing a revival in scientific and clinical research. When used under the appropriate guidance and setting, these substances show promise for substantially improving well-being and reducing mental ill-health alongside an excellent safety...
Abstract Background Scientific interest in the therapeutic effects of classical psychedelics has increased in the past two decades. The psychological effects of these substances outside the period of acute intoxication have not been fully characterized. This study aimed to: (1) quantify the effects of psilocybin, ayahuasca, and lysergic acid diethylamide (LSD) on psychological outcomes in the...
Abstract Objective To conduct a systematic review of modern‐era (post‐millennium) clinical studies assessing the therapeutic effects of serotonergic psychedelics drugs for mental health conditions. Although the main focus was on efficacy and safety, study characteristics, duration of antidepressants effects across studies, and the role of the subjective drug experiences were also reviewed and...
This chapter stresses how illicit drugs were difficult to obtain in America and were often heavily diluted by the early 1940s. It illustrates the conditions that limited the supply of drugs in the Unites States, such as the massive diversion of resources toward a single national effort, the militarization of almost every major sea passage, an extremely limited supply of private aircraft and...
This chapter focuses on psychedelics as another emerging front in the war over the war on drugs in the mid 2010s, with most psychedelic substances, such as LSD, mescaline, and psilocybin, being Schedule I listed since 1970. It explains how the scheduling imposed significant barriers to scientific research on hallucinogenic substances and their effects, through stringent security requirements,...