Zenodo (CERN European Organization for Nuclear Research)
February 21, 2026
Anthony W. Eckert
preprint
Applies the Void Framework to psychedelic-assisted therapy. Unique feature: the therapy deliberately induces temporary dissolution of the ego boundary — a controlled void state used therapeutically. The void is the mechanism, not the harm. Oregon and MAPS protocols as constraint implementations.
JURNAL RISET RUMPUN ILMU KEDOKTERAN
February 19, 2026
Aziz Alqadri Setiawan, Sulthan Rafi Abyan, Ahmad Fajar Sidik
Burnout is a psychological condition characterized by emotional exhaustion, depersonalization, and decreased personal achievement, commonly experienced by medical students. Mindfulness, defined as awareness and acceptance of the present moment without judgment, has been increasingly studied as a strategy to reduce burnout. This narrative literature review aims to evaluate the effectiveness of...
bioRxiv (Cold Spring Harbor Laboratory)
February 6, 2026
Haolong Wang
preprint
The mechanistic link between molecular pharmacology and global brain dynamics remains unresolved - a "scale bridge" problem central to consciousness research. We propose the Receptor-Constrained Dynamical Topology (RCDT) hypothesis: that the functional impact of neuromodulatory drugs propagates from local ligand-receptor binding events through spatially heterogeneous gain modulation to produce...
Preprints.org
February 6, 2026
Nicola De Pisapia, Andrea Polo, Andrea Signorelli
preprint
Immersive virtual environments are increasingly investigated as tools capable of modulating conscious experience, yet the specific contribution of graded immersion to altered states of consciousness (ASC), time perception, and cognition remains unclear. The present study examined how different levels of immersion during videogame play influence subjective experience and post-experience...
The MIT Press eBooks
February 3, 2026
How Should We Look for the Self?There is a long tradition in philosophy for asking about the nature and metaphysics of the self.David Hume famously observed that "when I enter most intimately into what I call myself . . .I never catch myself at any time without a perception, and never can observe any thing but the perception."Most would likely agree that the self is not easy to catch in...
Cambridge University Press eBooks
January 27, 2026
Z. Chen
6 citations
Mysticism refers to extraordinary experiences that transcend perceived reality and transform the individual. Section 1 introduces key features such as noetic and ineffable qualities, alongside psychological typologies and a fourfold hierarchy of mystical forms. Section 2 explores monistic mysticism, where self and ultimate reality merge in oneness and ego-dissolution, illustrated through...
medRxiv Preprint Server
January 13, 2026
Deniz Yilmaz, Lena Deller, Johanna Spaeth et al.
preprint
When the brain and body misalign, emotional experience and sense of reality can be disrupted. Although such atypical experiences are central to schizophrenia spectrum disorders (SSD), interoception, processing of internal bodily signals, remains poorly understood in individuals with SSD, particularly across subjective, behavioural, and neural domains. We tested whether SSD is associated with...
2026
Irina Dell'Orto
preprint
Background: Psilocybin-assisted therapy (PAT) has demonstrated rapid and substantial antidepressant effects in phase 2 RCTs (Davis et al., 2021; Carhart-Harris et al., 2021), and phase 3 trials are now active (Usona uAspire, NCT06308653). However, three critical gaps remain unresolved in 2025: (1) the durability of effects beyond 12 months has not been established in a controlled design; (2)...
OSF Preprints
2026
Edoardo Fiorino
preprint
This essay explores a naturalistic "middle way" between the traditional approaches to the existence of the soul—believing versus non-believing—and focuses on the related, ultimate question: what happens when we die? It navigates between the metaphysical assumptions of Cartesian dualism and the reductionism of strict scientism, utilizing the framework of Contextual Behavioral Science and Steven...
International Journal of English Language Education and Literature Studies
2026
Dr. Shruti Srivastava, Srishti Srishti
Whitman, the renowned 19th century American representative poet and Kabir, the acclaimed 15th century Indian mystic poet and singer have immensely contributed towards transformation of the inner self, the society and the world through their works which propagate the ideas and themes which are universally relevant and acclaimed. The paper would be a select study of how the themes and areas such...