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Libro Comunicaciones 2021
Descripción del caso: Mujer de 30 años traída a Urgencias tras encontrarla andando por la carretera. Hace 48h se encontraba en un retiro espiritual, consumiendo una cantidad indeterminada de ayahuasca. Ha permanecido en vigilia desde el consumo, con sensación de que si acaba cerrando los ojos puede morir. Se encuentra inquieta, con desinhibición conductual y en contexto de elevada angustia, se...
Libro Comunicaciones 2021
- Objetivos: Ayahuasca es una bebida compuesta por Banisteriopsis caapi, rica en β-carbolinas (harmina, tetrahidroharmina y harmalina) y Psychotria viridis, rica en dimetiltriptamina (DMT). β-carbolinas funcionan como inhibidores reversibles de la enzima monoaminooxidasa A, involucrada en la inhibición del metabolismo de DMT. DMT es un agonista parcial de los receptores de serotonina con...
Figshare 2021 Jeremy Weleff, Teddy J. Akiki, Brian S. Barnett preprint
Dataset for a bibliometric analysis of journal articles reporting findings from clinical studies of the psychedelics 5-methoxy-N, N-dimethyltryptamine (5-MeO-DMT), ayahuasca, dimethyltryptamine (DMT), ibogaine, lysergic acid diethylamide (LSD), mescaline, MDMA, and psilocybin published from 1965-2018.This data accompanies our article:Bibliometric Analysis of Academic Journal Articles Reporting...
Frontiers in Psychiatry 2021 Sylvana Vilca-Melendez, Malin V. Uthaug, Julian L Griffin 5 citations
While psychedelics may have therapeutic potential for treating mental health disorders such as depression, further research is needed to better understand their biological effects and mechanisms of action when considering the development of future novel therapy approaches. Psychedelic research could potentially benefit from the integration of metabonomics by proton nuclear magnetic resonance...
Revista del CESLA International Latin American Studies Review December 31, 2020 Robson Savoldi, Rodrigo de Azeredo Grünewald 2 citations
No Brasil, algumas plantas, bebidas e religiosidades são chamadas de jurema. Desde o período colonial, se registra o uso ritual da jurema entre indígenas do Nordeste do Brasil. Além disso, a jurema emerge com novas feições em uma religiosidade chamada catimbó, encadeada a partir daqueles ritos, e a qual foi alcançada pela umbanda em meados do século XX. A umbanda se reatualizou em contato com o...
ACS Pharmacology & Translational Science December 29, 2020 Michael B. Gatch, Adam C. Hoch, Theresa M. Carbonaro 13 citations
Novel synthetic compounds have been available for decades as quasi-legal alternatives to controlled substances. The hallucinogen-like effects of eight novel substituted tryptamines were evaluated to determine their potential abuse liability. Male Sprague-Dawley rats were trained to discriminate 2,5-dimethoxy-4-methylamphetamine (DOM, 0.5 mg/kg, i.p., 30 min) from saline....
ACS Pharmacology & Translational Science December 14, 2020 Adam K. Klein, Muhammad Chatha, Lauren J. Laskowski et al. 103 citations
The 5-HT2A receptor is thought to be the primary target for psilocybin (4-phosphoryloxy-N,N-dimethyltryptamine) and other serotonergic hallucinogens (psychedelic drugs). Although a large amount of experimental work has been conducted to characterize the pharmacology of psilocybin and its dephosphorylated metabolite psilocin (4-hydroxy-N,N-dimethyltryptamine), there has been little systematic...
December 10, 2020 Ordilena Ferreira de Miranda
\n B. caapi e P. viridis são plantas de origem amazônica e as principais espécies preconizados para preparação do chá Ayahuasca. Um chá com efeitos enteogênico e psicotrópico de uso milenar pelos povos indígenas da Amazônia, preparado pela decocção de caules de B. Caapi, que apresenta os alcaloides β-carbolínicos harmina (HRM), harmalina (HRL) e tetrahidrohramina (THH), e folhas de P. viridis...
International Journal of Molecular Sciences December 4, 2020 Sara Malaca, Alfredo Fabrizio Lo Faro, Alice Tamborra et al. 48 citations
Our understanding of tryptamines is poor due to the lack of data globally. Tryptamines currently are not part of typical toxicology testing regimens and their contribution to drug overdoses may be underestimated. Although their prevalence was low, it is increasing. There are few published data on the many new compounds, their mechanisms of action, onset and duration of action, toxicity, signs...
December 1, 2020 Caroline Mathon, Christèle Widmer, R. Mégevand et al.
Objectif Depuis de nombreuses annees, la politique en matiere de drogues est basee en Suisse sur quatre piliers, a savoir la prevention, la therapie, la repression et la reduction des risques. Parmi les actions mises en œuvre concernant la reduction des risques lies aux consommations recreatives de substances psychoactives, une nouvelle offre a ete proposee depuis 2019 a Geneve, consistant en...