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Depression: all studies

Page 934 of 1,034: studies 9,331 to 9,340 of 10,336, newest first. Back to the depression overview

Research

Novel Glutamatergic Treatments for Severe Mood Disorders.

Current behavioral neuroscience reports October 9, 2015 Minkyung Park, Mark J. Niciu, Carlos A. Zarate

All currently approved antidepressant medications for major depressive disorder (MDD) and bipolar disorder act primarily on the monoaminergic system and have varying affinities for serotonergic, norepinephrine-ergic, and/or dopaminergic receptors. Unfortunately, these drugs are only effective in approximately two-thirds of patients. Glutamate is the major excitatory neurotransmitter in the...

DOI: 10.1007/s40473-015-0050-5 (opens in new tab) Full text (opens in new tab) Glutamate Antagonist Mood disorders N-methyl-d-aspartate nmda +1

Impact of Mindfulness Training on Physiological Measures of Stress and Objective Measures of Attention Control in a Military Helicopter Unit

International Journal of Aviation Psychology October 2, 2015 Anders Meland, Kazuma Ishimatsu, Anne Marte Pensgaard et al. 54 citations

Objective: This study sought to determine if mindfulness training (MT) has a measurable impact on stress and attentional control as measured by objective physiological and psychological means.Background: Periods of persistent, intensive work demands are known to compromise recovery and attentional capacity. The effects of 4-month MT on salivary cortisol and performance on 2 computer-based...

The Mindfulness-to-Meaning Theory: Extensions, Applications, and Challenges at the Attention–Appraisal–Emotion Interface

Psychological Inquiry October 2, 2015 Eric L Garland, Norman A. S. Farb, Philippe R. Goldin et al. 228 citations

Over the past several decades, a corpus of research has emerged detailing the therapeutic outcomes and processes of mindfulness. The emergence of the field of contemplative science has given rise t...

DOI: 10.1080/1047840x.2015.1092493 (opens in new tab) Mindfulness Contemplation Meaning existential Appraisal theory +5

A review on how meditation could be used to comfort the terminally ill.

Palliative & Supportive Care October 2015 Michael Stephen Ball, Bryan Vernon

Our objective was to review how meditation could comfort the terminally ill. Our methodology was a literature search, which included books, journals, papers in collections, and online databases. The main search engines employed were Google Scholar and the Durham University Library. The main databases consulted were the Christian Meditation Centre, Project Meditation, and Stress-Related Facts...

A randomized controlled trial on the efficacy of mindfulness-based cognitive therapy and a group version of cognitive behavioral analysis system of psychotherapy for chronically depressed patients.

Journal of Consulting and Clinical Psychology October 2015 Johannes Michalak, Martin Schultze, Thomas Heidenreich et al.

Mindfulness-based cognitive therapy (MBCT) has recently been proposed as a treatment option for chronic depression. The cognitive behavioral analysis system of psychotherapy (CBASP) is the only approach specifically developed to date for the treatment of chronically depressed patients. The efficacy of MBCT plus treatment-as-usual (TAU), and CBASP (group version) plus TAU, was compared to TAU...

Fifteen minute consultation on children 'hearing voices': when to worry and when to refer.

Archives of disease in childhood. Education and practice edition October 2015 M Elena Garralda

Auditory hallucinations are uncommon paediatric presentations, but they can be alarming and lead to emergency consultations. This review outlines the phenomenology of auditory hallucinations, their assessment and clinical significance. Auditory hallucinations are seen in the course of acute medical disorders, often together with decreased levels of consciousness, as in febrile illness and in...

The effectiveness of mindfulness based programs in reducing stress experienced by nurses in adult hospital settings: a systematic review of quantitative evidence protocol.

JBI database of systematic reviews and implementation reports October 1, 2015 Elmarie Botha, Teri Gwin, Christina Purpora

The objective of this review is to identify the effectiveness of mindfulness based programs in reducing stress experienced by nurses in adult hospitalized patient care settings. Nursing professionals face extraordinary stressors in the medical environment. Many of these stressors have always been inherent to the profession: long work hours, dealing with pain, loss and emotional suffering,...

Mindfulness-based therapy for drug-resistant epilepsy: An assessor-blinded randomized trial.

Neurology September 29, 2015 Venus Tang, Wai S Poon, Patrick Kwan

To investigate the effectiveness of mindfulness-based therapy (MT) and social support (SS) in patients with drug-resistant epilepsy. We performed an assessor-blinded randomized control trial. Sixty patients with drug-resistant epilepsy were randomly allocated to MT or SS (30 per group). Each group received 4 biweekly intervention sessions. The primary outcome was the change in the total score...

THE PSYCHOMETRIC PROPERTIES OF TURKISH VERSION OF SELF TRANSCENDENCE SCALE

September 15, 2015 Hakan Sarıcam

ABSTRACT The aim of this research is to adapt the Self- transcendence Scale (Reed, 1991) to Turkish and to examine its psychometric properties. The study has two steps. The research was conducted on 517 participants who are 167 teachers and 350 university students in Sakarya University. The validity and reliability of scale was investigated by language equality, explanatory factor analysis,...

Age dependence of the rapid antidepressant and synaptic effects of acute NMDA receptor blockade

Frontiers in Molecular Neuroscience September 11, 2015 Elena Enosyreva, Anita E. Autry, Ege Ekavalali et al. 51 citations

Ketamine is a NMDA receptor antagonist that produces rapid antidepressant responses in individuals with major depressive disorder. The antidepressant action of ketamine has been linked to blocking NMDA receptor activation at rest, which inhibits eukaryotic elongation factor2 kinase leading to desuppression of protein synthesis and synaptic potentiation in the CA1 region of the hippocampus....