Journal of Occupational Health Psychology
February 1, 2019
Larissa Bartlett, Angela J. Martin, Amanda L. Neil et al.
This meta-analytic review responds to promises in the research literature and public domain about the benefits of workplace mindfulness training. It synthesizes randomized controlled trial evidence from workplace-delivered training for changes in mindfulness, stress, mental health, well-being, and work performance outcomes. Going beyond extant reviews, this article explores the influence of...
Psychiatry Research
February 1, 2019
Frank Larøi, Josef J Bless, Julien Laloyaux et al.
Epidemiological studies have repeatedly shown that a significant minority of the general population have experienced hallucinations, however, a potential effect of age on the prevalence of hallucinations in the general population has never been previously examined in a specific study. The aim of the present study was thus to examine the effects of age and sensory modality on hallucination...
Journal of Consulting and Clinical Psychology
February 1, 2019
Z. Segal, A. Anderson, Tahira Gulamani et al.
Background: To investigate whether usage of treatment-acquired regulatory skills is associated with prevention of depressive relapse/recurrence. Method: Remitted depressed outpatients entered a 24-month clinical follow up after either 8 weekly group sessions of cognitive therapy (CT; N = 84) or mindfulness-based cognitive therapy (MBCT; N = 82). The primary outcome was symptom return meeting...
Clinical Toxicology
February 1, 2019
Michael J Moss, Robert G Hendrickson
41 citations
Amanita muscaria (AM) and A. pantherina (AP) contain ibotenic acid and muscimol and may cause both excitatory and sedating symptoms. Gastrointestinal (GI) symptoms are not classically described but have been reported. There are relatively few reported cases of poisoning with these mushrooms in North America. This is a retrospective review of ingestions of ibotenic acid and muscimol containing...
January 31, 2019
In this meta-analysis of 10 randomized trials, ketamine was associated with rapid reduction of suicidal ideation, sometimes even without similar reductions in depression. The effect persisted for 7 days.
Frontiers in Psychology
January 28, 2019
M. Navarro-Haro, Marta Modrego-Alarcón, H. Hoffman et al.
Generalized Anxiety Disorder (GAD) is a very prevalent disorder in primary care (PC). Most patients with GAD never seek treatment, and those who do seek treatment often drop out before completing treatment. Although it is an understudied treatment, Mindfulness-Based Interventions (MBIs) indicate preliminary efficacy for the treatment of GAD symptoms, but many patients with GAD present other...
Neuropsychopharmacology
January 26, 2019
M. Madsen, Patrick M. Fisher, Daniel Burmester et al.
505 citations
The main psychedelic component of magic mushrooms is psilocybin, which shows promise as a treatment for depression and other mental disorders. Psychedelic effects are believed to emerge through stimulation of serotonin 2A receptors (5-HT2ARs) by psilocybin's active metabolite, psilocin. We here report for the first time the relationship between intensity of psychedelic effects, cerebral 5-HT2AR...
Evidence-Based Mental Health
January 23, 2019
Eve-Ling Khoo, Rebecca Small, Wei Cheng et al.
Question This review compares mindfulness-based stress reduction (MBSR) to cognitive-behavioural therapy (CBT) in its ability to improve physical functioning and reduce pain intensity and distress in patients with chronic pain (CP), when evaluated against control conditions. Study selection and analysis Ovid MEDLINE, EmbaseClassic+Embase, PsycINFO and the Cochrane Library were searched to...
January 23, 2019
Samuel T. Wilkinson
Define the therapeutic role of ketamine in depression and suicidal ideation. Outline the safety concerns related to the use of ketamine in psychiatric practice.
Nature Communications
January 15, 2019
Brendan Hare, R. Shinohara, Rong-Jian Liu et al.
Impaired function in the medial prefrontal cortex (mPFC) contributes to depression, and the therapeutic response produced by novel rapid-acting antidepressants such as ketamine are mediated by mPFC activity. The mPFC contains multiple types of pyramidal cells, but it is unclear whether a particular subtype mediates the rapid antidepressant actions of ketamine. Here we tested two major subtypes,...