Annals of Clinical Psychiatry
November 1, 2019
C. Ross, R. Jain, Carl J. Bonnett et al.
Introduction Combat veterans are at high risk for the development of posttraumatic stress disorder (PTSD) and substance use disorders. Ketamine has been shown to be an effective treatment for numerous mental health disorders, although research on its efficacy in combat-related PTSD in veterans is very limited. Methods The study population consisted of 30 US military veterans with combat-related...
2019 IEEE R10 Humanitarian Technology Conference (R10-HTC)(47129)
November 1, 2019
P. D. Purnamasari, Alya Fernandya
The desire to end someone's life commonly triggered by depression or mental health. One way to detect whether someone is depressed is by checking whether the person is constantly stressed for a long time. Electroencephalograph (EEG) is one of physiological signal that can be used for monitoring someone's mental condition, such as stress. The proposed and developed Stress Detection and...
The Oxford Handbook of Positive Emotion and Psychopathology
November 1, 2019
Nicole Geschwind, Saara Martinmäki, Eric L Garland
Positive emotions are vital to psychological well-being and enhance resilience against psychopathology. One of the psychiatric disorders most characterized by a lack of positive emotions is major depressive disorder. Despite the resilience-enhancing features of positive emotions and high rates of relapse for major depressive disorder, current recommended treatment forms do not pay much explicit...
Social Cognitive and Affective Neuroscience
November 1, 2019
Hedy Kober, Jason Buhle, Jochen Weber et al.
Mindfulness training ameliorates clinical and self-report measures of depression and chronic pain, but its use as an emotion regulation strategy-in individuals who do not meditate-remains understudied. As such, whether it (i) down-regulates early affective brain processes or (ii) depends on cognitive control systems remains unclear. We exposed meditation-naïve participants to two kinds of...
Pain Medicine
November 1, 2019
Melissa A Day, L Charles Ward, Dawn M Ehde et al.
AbstractObjectiveThis pilot trial compared the feasibility, tolerability, acceptability, and effects of group-delivered mindfulness meditation (MM), cognitive therapy (CT), and mindfulness-based cognitive therapy (MBCT) for chronic low back pain (CLBP).SettingUniversity of Queensland Psychology Clinic.SubjectsParticipants were N = 69 (intent-to-treat [ITT] sample) adults with CLBP.DesignA...
Neuropharmacology
November 1, 2019
Jun Yamada, Shozo Jinno
Recent studies have shown that ketamine, an open channel blocker of the N-methyl-d-aspartate receptor (NMDAR), is effective for patients with treatment-resistant depression. In this study, we aimed to elucidate the potential link between antidepressant-like effects of a single ketamine administration and dorsoventral differentiation in adult hippocampal neurogenesis. Immunohistochemical...
Psychopharmacology
November 1, 2019
Suzanne L. Russ, R L Carhart-Harris, Geoffrey Maruyama et al.
75 citations
Recent research demonstrated the potential of psychedelic drugs as treatment for depression and death-related anxiety and as an enhancement for well-being. While generally positive, responses to psychedelic drugs can vary according to traits, setting, and mental state (set) before and during ingestion. Most earlier models explain minimal response variation, primarily related to dosage and...
The Lancet Psychiatry
October 28, 2019
N. Black, E. Stockings, G. Campbell et al.
Background: Medicinal cannabinoids, including medicinal cannabis, pharmaceutical cannabinoids and their synthetic derivatives, including tetrahydrocannabinol (THC) and or cannabidiol (CBD), have been suggested to have a therapeutic role for certain mental health conditions. The primary objective was to review the evidence for cannabinoids in treating symptoms of depression, anxiety,...
BMC Psychiatry
October 28, 2019
Rafael G. Dos Santos, José Carlos Bouso, Jaime E. C. Hallak
17 citations
In a recent issue of the BMC Psychiatry, the evidence of effectiveness of treatments for psychiatric conditions in end-stage cancer patients was reviewed (Johnson, 2018). The review was comprehensive, and included traditional and non-traditional/alternative treatments, including herbal medicines and spirituality. However, evidence showing that classic or serotonergic hallucinogens/psychedelics...
Journal of Psychoactive Drugs
October 24, 2019
Toby Lea, Nicole Amada, Henrik Jungaberle
121 citations
Self-administration of very low doses of psychedelic drugs to improve mental health and wellbeing and enhance cognitive function, known as microdosing, has received recent media attention, but little research has been conducted. We conducted a content analysis of discussions about microdosing from the online forum Reddit. We examined motivations, dosing practices, and perceived benefits and...