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Depression: all studies

Page 843 of 1,036: studies 8,421 to 8,430 of 10,358, newest first. Back to the depression overview

Research

High-Dose Ketamine Infusion for the Treatment of Posttraumatic Stress Disorder in Combat Veterans

Annals of Clinical Psychiatry November 1, 2019 C. Ross, R. Jain, Carl J. Bonnett et al.

Introduction Combat veterans are at high risk for the development of posttraumatic stress disorder (PTSD) and substance use disorders. Ketamine has been shown to be an effective treatment for numerous mental health disorders, although research on its efficacy in combat-related PTSD in veterans is very limited. Methods The study population consisted of 30 US military veterans with combat-related...

Real Time EEG-based Stress Detection and Meditation Application with K-Nearest Neighbor

2019 IEEE R10 Humanitarian Technology Conference (R10-HTC)(47129) November 1, 2019 P. D. Purnamasari, Alya Fernandya

The desire to end someone's life commonly triggered by depression or mental health. One way to detect whether someone is depressed is by checking whether the person is constantly stressed for a long time. Electroencephalograph (EEG) is one of physiological signal that can be used for monitoring someone's mental condition, such as stress. The proposed and developed Stress Detection and...

Facilitation of Positive Emotions Through Mindfulness-Based Therapy

The Oxford Handbook of Positive Emotion and Psychopathology November 1, 2019 Nicole Geschwind, Saara Martinmäki, Eric L Garland

Positive emotions are vital to psychological well-being and enhance resilience against psychopathology. One of the psychiatric disorders most characterized by a lack of positive emotions is major depressive disorder. Despite the resilience-enhancing features of positive emotions and high rates of relapse for major depressive disorder, current recommended treatment forms do not pay much explicit...

Let it be: mindful acceptance down-regulates pain and negative emotion.

Social Cognitive and Affective Neuroscience November 1, 2019 Hedy Kober, Jason Buhle, Jochen Weber et al.

Mindfulness training ameliorates clinical and self-report measures of depression and chronic pain, but its use as an emotion regulation strategy-in individuals who do not meditate-remains understudied. As such, whether it (i) down-regulates early affective brain processes or (ii) depends on cognitive control systems remains unclear. We exposed meditation-naïve participants to two kinds of...

A Pilot Randomized Controlled Trial Comparing Mindfulness Meditation, Cognitive Therapy, and Mindfulness-Based Cognitive Therapy for Chronic Low Back Pain

Pain Medicine November 1, 2019 Melissa A Day, L Charles Ward, Dawn M Ehde et al.

AbstractObjectiveThis pilot trial compared the feasibility, tolerability, acceptability, and effects of group-delivered mindfulness meditation (MM), cognitive therapy (CT), and mindfulness-based cognitive therapy (MBCT) for chronic low back pain (CLBP).SettingUniversity of Queensland Psychology Clinic.SubjectsParticipants were N = 69 (intent-to-treat [ITT] sample) adults with CLBP.DesignA...

Potential link between antidepressant-like effects of ketamine and promotion of adult neurogenesis in the ventral hippocampus of mice.

Neuropharmacology November 1, 2019 Jun Yamada, Shozo Jinno

Recent studies have shown that ketamine, an open channel blocker of the N-methyl-d-aspartate receptor (NMDAR), is effective for patients with treatment-resistant depression. In this study, we aimed to elucidate the potential link between antidepressant-like effects of a single ketamine administration and dorsoventral differentiation in adult hippocampal neurogenesis. Immunohistochemical...

Replication and extension of a model predicting response to psilocybin.

Psychopharmacology November 1, 2019 Suzanne L. Russ, R L Carhart-Harris, Geoffrey Maruyama et al. 75 citations

Recent research demonstrated the potential of psychedelic drugs as treatment for depression and death-related anxiety and as an enhancement for well-being. While generally positive, responses to psychedelic drugs can vary according to traits, setting, and mental state (set) before and during ingestion. Most earlier models explain minimal response variation, primarily related to dosage and...

Cannabinoids for the treatment of mental disorders and symptoms of mental disorders: A systematic review and meta-analysis

The Lancet Psychiatry October 28, 2019 N. Black, E. Stockings, G. Campbell et al.

Background: Medicinal cannabinoids, including medicinal cannabis, pharmaceutical cannabinoids and their synthetic derivatives, including tetrahydrocannabinol (THC) and or cannabidiol (CBD), have been suggested to have a therapeutic role for certain mental health conditions. The primary objective was to review the evidence for cannabinoids in treating symptoms of depression, anxiety,...

Serotonergic hallucinogens/psychedelics could be promising treatments for depressive and anxiety disorders in end-stage cancer

BMC Psychiatry October 28, 2019 Rafael G. Dos Santos, José Carlos Bouso, Jaime E. C. Hallak 17 citations

In a recent issue of the BMC Psychiatry, the evidence of effectiveness of treatments for psychiatric conditions in end-stage cancer patients was reviewed (Johnson, 2018). The review was comprehensive, and included traditional and non-traditional/alternative treatments, including herbal medicines and spirituality. However, evidence showing that classic or serotonergic hallucinogens/psychedelics...

Psychedelic Microdosing: A Subreddit Analysis

Journal of Psychoactive Drugs October 24, 2019 Toby Lea, Nicole Amada, Henrik Jungaberle 121 citations

Self-administration of very low doses of psychedelic drugs to improve mental health and wellbeing and enhance cognitive function, known as microdosing, has received recent media attention, but little research has been conducted. We conducted a content analysis of discussions about microdosing from the online forum Reddit. We examined motivations, dosing practices, and perceived benefits and...