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Depression: all studies

Page 818 of 1,034: studies 8,171 to 8,180 of 10,336, newest first. Back to the depression overview

Research

Mindfulness-based stress reduction and mindfulness-based cognitive therapy for psychological health and well-being in nonclinical samples: A systematic review and meta-analysis.

International Journal of Stress Management November 1, 2020 Dawn Querstret, L. Morison, Sophie Dickinson et al.

Much of the burden associated with poor mental health is associated with symptom experience in the general population. We conducted a systematic review and meta-analysis of studies conducted in non-clinical samples, evaluating Mindfulness-Based Programs (MBPs) for outcomes related to psychological health and well-being. We focussed on Mindfulness-Based Stress Reduction (MBSR) and...

Clinical phenomenology of the prodrome for psychosis

Oxford University Press eBooks November 1, 2020 Albert R. Powers, Thomas H. McGlashan, S. Woods 5 citations

More than 100 years of retrospective studies show that psychosis is usually preceded by a prodrome. Nonspecific symptoms such as anxiety and depression precede more specific negative and attenuated positive symptoms. Prospective diagnostic criteria have been developed based on the retrospective work. The prospective criteria have shown high reliability in the research context, and follow-up...

The effect of intravenous, intranasal, and oral ketamine in mood disorders: A meta-analysis.

Journal of Affective Disorders November 1, 2020 Roger S McIntyre, Isabelle P. Carvalho, Leanna M.W. Lui et al. 186 citations

BACKGROUND Ketamine is established as a rapid and effective treatment in adults with treatment-resistant depression (TRD). The availability of different formulations and routes of delivery invites the need for evaluating relative effect sizes. METHODS Effect size with respect to depression symptom reduction for each formulation and route of delivery was compared at discrete time-points (i.e.,...

Me, myself, bye: regional alterations in glutamate and the experience of ego dissolution with psilocybin.

Neuropsychopharmacology November 1, 2020 Natasha L. Mason, K P C Kuypers, F Müller et al. 261 citations

There is growing interest in the therapeutic utility of psychedelic substances, like psilocybin, for disorders characterized by distortions of the self-experience, like depression. Accumulating preclinical evidence emphasizes the role of the glutamate system in the acute action of the drug on brain and behavior; however this has never been tested in humans. Following a double-blind,...

A Narrative Study of the Five Senses Meditation of the Adolescent Suffering from Abandonment Anxiety

October 31, 2020 Kyung-Min Ahn

This study aimed to investigate on the effect of the Five Senses Meditation to an adolescent suffering from abandonment anxiety. The subject of the study is a student attending a high school in P-city and has an experience of being raised by several foster parents from childhood. This study focused on searching for the root and context of the pain by facing, discerning, and accepting...

Using mindfulness to improve quality of life in caregivers of individuals with intellectual disabilities and autism spectrum disorder.

International journal of developmental disabilities October 27, 2020 Nirbhay N. Singh, Giulio E. Lancioni, Oleg N. Medvedev et al.

Objectives: Caring for individuals with intellectual disabilities (ID) or autism spectrum disorder (ASD) can be gratifying as well as stressful. Professional staff employed as caregivers often report compromised mental and physical wellbeing due to the stressful nature of working with clients who exhibit aggressive and destructive behaviors. Prolonged work-related stress results in diminished...

Candidate Strategies for Development of a Rapid-Acting Antidepressant Class That Does Not Result in Neuropsychiatric Adverse Effects: Prevention of Ketamine-Induced Neuropsychiatric Adverse Reactions

International Journal of Molecular Sciences October 26, 2020 Motohiro Okada, Yasuhiro Kawano, Kouji Fukuyama et al. 31 citations

Non-competitive N-methyl-D-aspartate/glutamate receptor (NMDAR) antagonism has been considered to play important roles in the pathophysiology of schizophrenia. In spite of severe neuropsychiatric adverse effects, esketamine (racemic enantiomer of ketamine) has been approved for the treatment of conventional monoaminergic antidepressant-resistant depression. Furthermore, ketamine improves...

Changes in hair cortisol and self-reported stress measures following mindfulness-based stress reduction (MBSR): A proof-of-concept study in pediatric hematology-oncology professionals.

Complementary Therapies in Clinical Practice October 23, 2020 Martin Lamothe, Émélie Rondeau, Michel Duval et al.

BACKGROUND AND PURPOSE Little data is available on the effect of mindfulness amongst pediatric hematology-oncology professionals. The purpose was to further document change in biological and psychological stress following a mindfulness-based stress reduction (MBSR) program. MATERIALS AND METHODS We led two pre-post interventional studies (n = 12 and n = 25) and measured changes on hair cortisol...

Differential effects of mindfulness meditation conditions on repetitive negative thinking and subjective time perspective: a randomized active-controlled study

Psychology and Health October 23, 2020 Susanna Feruglio, Alessio Matiz, Alessandro Grecucci et al.

Abstract Objective Preliminary findings suggest that different kinds of meditation could work on diverse cognitive and psychological processes. The present study aimed at disentangling the effects of three mindfulness techniques on mental rumination and subjective time perspective. Design: 75 young healthy participants were randomly assigned to one of four conditions: mindful breathing, body...

Treatment of a Complex Personality Disorder Using Repeated Doses of LSD—A Case Report on Significant Improvements in the Absence of Acute Drug Effects

Frontiers in Psychiatry October 22, 2020 Felix Müller, Markus Mühlhauser, Friederike Holze et al. 31 citations

A 39-year-old female patient suffering from severe, treatment-resistant depression and other symptoms associated with a complex personality disorder was admitted to our open psychiatric ward for an experimental treatment with lysergic acid diethylamide (LSD). The substance was administered in repeated weekly and ascending doses. Curiously, there were no substantial acute subjective effects of...