Scientific Reports
November 24, 2020
Julane Andries, Lisa Jerome, Evan Sola et al.
170 citations
Abstract The success of modern medicine creates a growing population of those suffering from life-threatening illnesses (LTI) who often experience anxiety, depression, and existential distress. We present a novel approach; investigating MDMA-assisted psychotherapy for the treatment of anxiety in people with an LTI. Participants with anxiety from an LTI were randomized in a double-blind study to...
Global Advances in Health and Medicine
November 23, 2020
Brenna K Novak, Anna Gebhardt, Harini Pallerla et al.
Background: Positive effects of mind-body skills programs on participant well-being have been reported in health professions students. The success seen with medical students at this university led to great interest in expanding the mind-body skills program so students in other disciplines could benefit from the program. Objective: The purpose of this study was to assess the effects of a 9-week...
Nepal Journal of Multidisciplinary Research
November 23, 2020
Tej Bahadur Karki, Kalpana Khadka
Suicide is a social phenomenon and is mainly caused by mental disorder which may be attributed to by genetic, neurotic, and environmental constructs. A total of 5,124 people had committed suicide in the fiscal year 2016/17.The number rose to 5,317 in 2017/18 and to 5,785 in 2018/19. Various social and biological factors have significant roles to create the suicidal thought in depressed people....
Psychopharmacology
November 21, 2020
Allison A. Feduccia, Lisa Jerome, Michael C Mithoefer et al.
39 citations
Retracted
Abstract Rationale MDMA-assisted psychotherapy is under investigation as a novel treatment for posttraumatic stress disorder (PTSD). The primary mechanism of action of MDMA involves the same reuptake transporters targeted by antidepressant medications commonly prescribed for PTSD. Objectives Data were pooled from four phase 2 trials of MDMA-assisted psychotherapy. To explore the effect of...
Journal of Student Research
November 20, 2020
Rebeccah Fleischmann, Michael I Posner
70% of high school students see anxiety and depression as a “major problem” among their peers (Pew Research Center). Meditation decreases anxiety and stress according to Harvard researchers. Stress and memory are very much connected as a recent study concluded that non-stressed people remember more items on average than stressed people. Although several studies have been done on the impacts of...
Southern African Journal of Anaesthesia and Analgesia
November 19, 2020
S Mayet
3 citations
Psychedelic substances have traditionally been used in medicine and religious rituals. Their use dates back thousands of years with fossil evidence as old as 10 000 years. Throughout the 1950s and 1960s psychedelics were used in clinical studies. These drugs then saw widespread use in hippie culture and were viewed as a drug of abuse with no medicinal value. Currently, psychedelics are being...
BMJ Open
November 12, 2020
Marloes J. Huijbers, Carolien Wentink, Anne E. M. Speckens et al.
Objectives This study aimed to explore predictors and outcomes associated with different trajectories of discontinuing antidepressant medication (ADM), in recurrently depressed individuals after participation in mindfulness-based cognitive therapy (MBCT). Facilitators and barriers of discontinuation were explored qualitatively.Design Mixed-methods study combining quantitative and qualitative...
JMIR Mental Health
November 12, 2020
A Mobile Health Mindfulness Intervention for Women With Moderate to Moderately Severe Postpartum Depressive Symptoms: Feasibility Study.
L'Encephale
November 12, 2020
Hugo Bottemanne, Anne Claret, Philippe Fossati
10 citations
The hypothesis of monoaminergic deficiency has long dominated the conceptual framework for the development of new antidepressant strategies, but the limits of conventional antidepressant treatments targeting monoaminergic signaling have motivated the search for new antidepressant pathways. The success of ketamine in the management of depressive disorders has provoked a renewed interest in...
International Journal of Bipolar Disorders
November 11, 2020
Imke Hanssen, Nicole Van der Horst, Marieke Boele et al.
Mindfulness- Based Cognitive Therapy (MBCT) could be a promising psychosocial intervention for people with bipolar disorder (BD). However, little is known about the feasibility of MBCT for people with BD. In this study we explore the facilitators and barriers people with BD experience of an adapted MBCT program. This qualitative study is part of a large, multicenter randomized controlled trial...