Scientific Reports
June 30, 2022
Jacopo Lamanna, Francesco Isotti, Mattia Ferro et al.
Unpredictable chronic mild stress (CMS) is among the most popular protocols used to induce depressive-like behaviors such as anhedonia in rats. Differences in CMS protocols often result in variable degree of vulnerability, and the mechanisms behind stress resilience are of great interest in neuroscience due to their involvement in the development of psychiatric disorders, including major...
Healthcare
June 29, 2022
Chiara Failla, Flavia Marino, Luca Bernardelli et al.
Mindfulness is one of the most popular psychotherapeutic techniques that help to promote good mental and physical health. Combining mindfulness with immersive virtual reality (VR) has been proven to be especially effective for a wide range of mood disorders for which traditional mindfulness has proven valuable. However, the vast majority of immersive VR-enhanced mindfulness applications have...
Cureus
June 28, 2022
Ann M. Inouye, Aaron Wolfgang
5 citations
The Food and Drug Administration (FDA) granted breakthrough therapy status to 3,4-methylenedioxymethamphetamine-assisted therapy (MDMA-AT) in 2017 due to preliminary evidence supporting its efficacy and safety in treating post-traumatic stress disorder (PTSD). A series of six phase-II clinical trials studying MDMA-AT for treatment-resistant PTSD found that 54% of MDMA-AT full-dose...
Frontiers in Pharmacology
June 28, 2022
Nataliya S. Vorobyeva, Alena A. Kozlova
16 citations
Classical psychedelics represent a family of psychoactive substances with structural similarities to serotonin and affinity for serotonin receptors. A growing number of studies have found that psychedelics can be effective in treating various psychiatric conditions, including post-traumatic stress disorder, major depressive disorder, anxiety, and substance use disorders. Mental health disorders...
Journal of Human Growth and Development
June 23, 2022
Dara Fernanda Brito Duarte, Jaiany Rodrigues Libório, Giovana Macêdo Egídio Cavalcante et al.
28 citations
Introduction: the public health crisis caused by COVID-19, a disease caused by SARS-CoV-2, has imposed physical threats and psychological suffering on both infected patients and individuals who experience social isolation and various governmental restrictions, leading to the appearance of symptoms like anxiety, depression, as well as insomnia, stress, and changes in biological rhythm. In face...
American Journal of Psychiatry
June 22, 2022
Lauren A M Lebois, N. Harnett, S. V. van Rooij et al.
Objective: Dissociation, a disruption or discontinuity in psychological functioning, is often linked with worse psychiatric symptoms; however, the prognostic value of dissociation after trauma is inconsistent. Determining whether trauma-related dissociation is uniquely predictive of later outcomes would enable early identification of at-risk trauma populations. We completed the largest...
Sustainability
June 21, 2022
Nicholas Tze Ping Pang, Eugene Boon Yau Koh, Mohd Amiruddin Mohd Kassim et al.
7 citations
Introduction: Performance anxiety is a transdiagnostic construct similar in both sports and clinical medical examinations. Given that acceptance and commitment therapy (ACT) and other similar therapies have transdiagnostic evidence in improving the performance of athletes, the same approach can be adopted for medical students in improving their performance during clinical examinations. This...
Research, Society and Development
June 21, 2022
Marcelo Vilela Machado João, Marcelo Demarzo, Ysao Yamamura et al.
2 citations
Background and aims: Evaluate the effects of the use of abbreviated mindfulness and acupuncture in healthy individuals, evaluating the levels of depression, anxiety, and life quality in an outpatient clinic of a Brazilian federal university. Methods: Comparison of two abbreviated interventions (mindfulness- and acupuncture-based) in a non-randomized pragmatic feasibility pilot study, with...
The international tinnitus journal
June 21, 2022
Chanchai Jariengprasert, Kasinee Watanapornmongkol, Sivaporn Kiatthanabumrung et al.
Mindfulness-based cognitive therapy (MBCT) has been suggested as an effective modality in reducing the effects of tinnitus and improving quality of life. This article aimed to compare the effectiveness of MBCT with that of standard treatment in the management of tinnitus in Thai patients. All participants were voluntarily divided into experimental MBCT and control groups depending on their...
Neuropsychopharmacology
June 21, 2022
Gitte M. Knudsen
56 citations
The serotonergic classical psychedelics include compounds that primarily activate the brain's serotonin 2 A receptor (5-HT2AR), such as LSD, psilocybin, and DMT (ayahuasca). The acute effects of these compounds are well-known as are their ability to increase the emotional state both in healthy people and in those with neuropsychiatric disorders. In particular psilocybin, the psychoactive...