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Depression: all studies

Page 654 of 1,034: studies 6,531 to 6,540 of 10,336, newest first. Back to the depression overview

Research

Older Adults in Psychedelic-Assisted Therapy Trials: A Systematic Review

European Psychiatry April 1, 2024 N. Kabir, B. Anderson, Lisa Bouchet et al. 1 citation

Introduction Growing clinical interest in psychedelic-assisted therapies has led to a second wave of research involving psilocybin, LSD, MDMA and other substances. Data suggests that these compounds have the potential to treat mental health conditions that are especially prevalent in older adults such as depression, anxiety, existential distress and post-traumatic stress disorder. Objectives...

Low-dose ketamine safely reduces acute pain in the ED with a more rapid and shorter effect than morphine.

Annals of Internal Medicine April 1, 2024 Evan S Schwarz

Guo J, Zhao F, Bian J, et al. Low-dose ketamine versus morphine in the treatment of acute pain in the emergency department: a meta-analysis of 15 randomized controlled trials. Am J Emerg Med. 2024;76:140-149. 38071883.

DOI: 10.7326/J24-0017 (opens in new tab) Full text (opens in new tab) Pain management Emergency medicine Ketamine therapy Analgesics +1

Potentiation of antidepressant effects: NPY1R agonist and ketamine synergy enhances TrkB signaling and neurogenesis in the ventral hippocampus.

Expert Opinion on Therapeutic Targets April 1, 2024 Carlos Arrabal-Gómez, Pedro Serrano-Castro, Jose Andrés Sánchez-Pérez et al. 7 citations

Major Depressive Disorder (MDD) poses a significant challenge to global health, with current treatments often limited by efficacy and onset delays. This study explores the synergistic antidepressant-like effects of an NPY1R agonist and Ketamine, targeting their neurobiological interactions within the ventral hippocampus. Utilizing a preclinical model, this study administered Neuropeptide Y...

DOI: 10.1080/14728222.2024.2342524 (opens in new tab) Full text (opens in new tab) Neurogenesis Antidepressant therapy Npy1r agonist Ventral hippocampus +9

Psilocybin analog 4-OH-DiPT enhances fear extinction and GABAergic inhibition of principal neurons in the basolateral amygdala.

Neuropsychopharmacology April 1, 2024 Thomas J. Kelly, Emma M. Bonniwell, Lianwei Mu et al. 26 citations

Psychedelics such as psilocybin show great promise for the treatment of depression and PTSD, but their long duration of action poses practical limitations for patient access. 4-OH-DiPT is a fast-acting and shorter-lasting derivative of psilocybin. Here we characterized the pharmacological profile of 4-OH-DiPT and examined its impact on fear extinction learning as well as a potential mechanism...

DOI: 10.1038/s41386-023-01744-8 (opens in new tab) Full text (opens in new tab) Psychopharmacology Anxiety-treatment Fear-response Brain-chemistry

Greater subjective effects of a low dose of LSD in participants with depressed mood.

Neuropsychopharmacology April 1, 2024 Hanna Molla, Royce Lee, Ilaria Tare et al. 37 citations

Recent studies and anecdotal reports suggest that psychedelics can improve mood states, even at low doses. However, few placebo-controlled studies have examined the acute effects of low doses of LSD in individuals with psychiatric symptoms. In the current study, we examined the acute and sub-acute effect of a low dose of LSD (26 µg) on subjective effects and mood in volunteers with mild...

Self-Rated Effectiveness of Ayahuasca and Breathwork on Well-Being, Psychological Resilience, Self-Compassion, and Personality: An Observational Comparison Study

Psychoactives March 31, 2024 Rishma S. I. Khubsing, Martin van Leerdam, Eline Haijen et al. 3 citations

Background: In recent years, there has been a growing interest in the therapeutic potential of classical psychedelics like ayahuasca for mental health improvement. Naturalistic studies at ayahuasca retreats have shown (short-term) improvements in mental well-being but understanding the psychological mechanisms is crucial. We are interested in psychological processes such as resilience,...

The role of metaphor in shamanism and poetry as a therapeutic tool for healing

World Journal of Advanced Research and Reviews March 30, 2024 Nawa Raj Subba

This paper explores the healing power of metaphor in indigenous shamanism and contemporary poetry. It explores how metaphor bridges the landscape, communicates emotions, and advances healing across cultures and languages. Analyzing specific examples from diverse shamanic traditions and contemporary poems reveals shared themes and unique approaches to metaphorical usage. The paper presents...

Pengaruh intervensi Mindfulness-Based Stress Reduction (MBSR) terhadap kecenderungan baby blues pada ibu postpartum

Procedia : Studi Kasus dan Intervensi Psikologi March 30, 2024 Nur Arrad Tenri Gangka, Kartika Cahyaningrum

Baby blues are a common disorder experienced by women in the postpartum period. Baby blues are classified as mild postpartum depression but if left untreated can develop into postpartum depression. Mindfulness-Based Stress Reduction (MBSR) is an intervention used to treat various psychological disorders such as stress, anxiety, and postpartum depression. This study aims to determine the effect...

Centering prayer in the treatment of bipolar disorder

World Journal of Advanced Research and Reviews March 30, 2024 Yanín Machado, Mauricio Chinchilla, Robert Hesse et al.

Bipolar Disorder (BD), formerly manic-depressive illness or manic depression, is a lifelong mood disorder and mental health condition that causes intense shifts in mood, energy levels, thinking patterns, and behavior. These shifts can last for hours, days, weeks, or months, interrupting the ability to carry out daily tasks. The condition is manageable with medications, talk therapy, lifestyle...

DOI: 10.30574/wjarr.2024.21.3.0981 (opens in new tab) Full text (opens in new tab) Prayer Bipolar disorder Psychotherapist Religious studies +1

Review of new evidence on effectiveness of different methods of lucid dream induction

International Journal of Medicine and Psychology March 28, 2024 О.в. Бодров

осознанные сновидения определяются как сны, в которых человек осознаёт, что спит, и при этом продолжает видеть сон. Прошло 11 лет с момента публикации предыдущего обзора эффективности методов индукции осознанных сновидений, поэтому настоящее исследование было направлено на обзор публикаций за последние 11 лет. Вторая цель состояла в повышении методологического качества исследований, включённых...