Canadian Journal on Aging
June 1, 2024
Sandrine Kalenzaga, David Clarys
La maladie d'Alzheimer se manifeste par des troubles de la mémoire et un déclin cognitif plus général, le plus souvent associés à des troubles de l'humeur et du comportement. Les traitements médicamenteux ayant une efficacité assez modeste, il apparaît nécessaire de leur associer une prise en charge non pharmacologique. La méditation de pleine conscience, qui a des effets bénéfiques sur le...
AIDS and behavior
June 1, 2024
Judith T. Moskowitz, Brijesh Sharma, Shireen Javandel et al.
2 citations
The growing number of people aging with HIV represents a group vulnerable to the symptom burdens of HIV-associated neurocognitive disorder (HAND). Among younger groups, Mindfulness-Based Stress Reduction (MBSR) has been shown to help people living with HIV manage HIV-related and other life stress, and although there is some theoretical and empirical evidence that it may be effective among those...
Obstetrics and gynecology clinics of North America
June 1, 2024
Lori A Brotto, Melanie Altas
5 citations
Mindfulness is defined as present-moment, nonjudgmental awareness. By reducing self-criticism, and depression, and increasing self-compassion, attention, and interoceptive awareness, mindfulness has been found across a variety of systematic reviews and meta-analyses to significantly improve sexual desire, sexual pain, and sex-related distress. It helps individuals connect with their bodies,...
CHEST critical care
June 1, 2024
Christopher E Cox, John A Gallis, Maren K Olsen et al.
3 citations
Psychological distress symptoms are present and persistent among many patients who survive a critical illness like COVID-19. Could a self-directed mobile app-delivered mindfulness intervention be feasibly and rapidly implemented within a clinical trials network to reduce distress symptoms? A randomized clinical trial was conducted between January 2021 and May 2022 at 29 US sites and included...
Pharmacological Reports
June 1, 2024
Agnieszka Pałucha-Poniewiera, Anna Rafało-Ulińska, Michal Santocki et al.
8 citations
Partial negative allosteric modulators (NAM) of the metabotropic glutamate 5 (mGlu5) receptor are an excellent alternative to full antagonists and NAMs because they retain therapeutic effects and have a much broader therapeutic window. Here, we investigated whether partial mGlu5 NAM, 2-(2-(3-methoxyphenyl)ethynyl)-5-methylpyridine (M-5MPEP), induced a fast and sustained antidepressant-like...
Psychedelic Medicine
June 1, 2024
Abshir S Adam, Kayleigh S. Lamalfa, Yasaman Razavi et al.
6 citations
Frontline antidepressants such as selective serotonin reuptake inhibitors (SSRIs) leave many patients with unmet treatment needs. Moreover, even when SSRIs reduce depressive symptoms, anhedonia, the loss of pleasure to previously rewarding activities, often remains unabated. This state of affairs is disheartening and calls for the development of medications to more directly treat anhedonia. The...
British Journal of Pharmacology
June 1, 2024
Isabel Werle, Laura M M Nascimento, Aymee L A Dos Santos et al.
21 citations
Ayahuasca (AYA) is a botanical psychedelic with promising results in observational and small clinical trials for depression, trauma and drug use disorders. Its psychoactive effects primarily stem from N,N-dimethyltryptamine (DMT). However, there is a lack of research on how and where AYA acts in the brain. This study addressed these questions by examining the extinction of aversive memories in...
TOGÜ Sağlık Bilimleri Dergisi
May 31, 2024
Merve Ataç, Dilek Avcı
Purpose: This study was conducted to examine the randomized controlled studies investigating the effects of mindfulness-based training programs given to nurses on occupational stress and to systematically evaluate the data obtained from the studies. Methods: In order to determine the effect of mindfulnessbased training programs on occupational stress in nurses, PubMed, Web of Science, Science...
BMC Anesthesiology
May 31, 2024
Xin Luo, Wen-Wen Hao, Xue Zhang et al.
7 citations
Propofol is effective and used as a kind of routine anesthetics in procedure sedative anesthesia (PSA) for ureteroscopy. However, respiratory depression and unconscious physical activity always occur during propofol-based PSA, especially in elderly patients. Esketamine has sedative and analgesic effects but without risk of cardiorespiratory depression. The purpose of this study is to...
Microbial Biosystems
May 30, 2024
Juan Camilo Rodriguez Martinez
The Tayrona were an indigenous tribe that lived in the Sierra Nevada de Santa Marta and its surroundings on the actual north territory of Colombia. The purpose of the present paper is to suggest the possibility of mushroom use in sacred rituals for spiritual purposes by the Tayrona in pre-hispanic Colombia, this obviously involving a mycological knowledge that would have included uses of fungi...