Ayahuasca-enhanced extinction of fear behaviour: Role of infralimbic cortex 5-HT2A and 5-HT1A receptors.
British Journal of Pharmacology June 1, 2024 Isabel Werle, Laura M M Nascimento, Aymee L A Dos Santos et al. 21 citations
Ayahuasca (AYA) is a botanical psychedelic with promising results in observational and small clinical trials for depression, trauma and drug use disorders. Its psychoactive effects primarily stem from N,N-dimethyltryptamine (DMT). However, there is a lack of research on how and where AYA acts in the brain. This study addressed these questions by examining the extinction of aversive memories in...
DOI: 10.1111/bph.16315 (opens in new tab)
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PTSD
Neuroplasticity
5‐hydroxytryptamine
Medial prefrontal cortex
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