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Depression: all studies

Page 493 of 1,037: studies 4,921 to 4,930 of 10,363, newest first. Back to the depression overview

Research

Combining Digital Cognitive Behavioral Therapy With Mindfulness Training for Binge Eating Disorder: Protocol for a Feasibility Trial

JMIR Research Protocols April 17, 2026 Margaret Sala, Corey Roos, Dante Ascarrunz et al.

BackgroundCognitive behavioral therapy (CBT) is the most effective treatment for binge eating disorder (BED) but is limited by modest efficacy and low reach of in-person delivery. Combining mindfulness training with CBT could enhance efficacy by targeting emotion dysregulation, a key factor in BED that CBT does not adequately target. Digital delivery can enhance the reach of treatment....

Producción de alcaloides en Psilocybe cubensis: aportes desde la bioquímica del Triptófanoy la sustentabilidad

CIENCIA EN DESARROLLO April 16, 2026 Brenda M. Delgado Melgarejo, Gerardo A. Caicedo

Esta revisión analiza cómo la suplementación con L-triptófano en el sustrato de cultivo de Psilocybe cubensis potencia la biosíntesis de psilocibina vía las enzimas PsiD, PsiH, PsiK y PsiM, alcanzando aumentos significativos en laconcentración alcaloide respecto a controles sin suplemento.La psilocibina después de ser ingerida se convierte en psilocina por un proceso de desfosforilación, que...

Yoga and the Mind-Body Connection

Improving Mental Well-Being at the Intersection of Mindfulness, Meditation, and Yoga April 16, 2026 Dilshith Azeezul Kabeer, W. Vinu, K. K. Shareef et al.

The chapter presents a unified examination of yoga and its body-mind approach by exploring neural mechanisms, psychological and philosophical aspects. It examines how yoga facilitates the body-mind connection through yogic texts and scientific study, such as breath regulation (pranayama), postural awareness (asana) and meditative focus (dhyana). This study applies polyvagal theory,...

Finding flow: Cultivating flow states as a counterpoint to depressive rumination.

Clinical Psychology Science and Practice April 16, 2026 Henrietta Roberts, Nicholas J. Moberly, Katie E Wood et al.

The defining feature of emotion regulation is the activation of a goal to influence the trajectory of emotion.Emotion regulation strategies often involve efforts to either decrease negative emotions or increase positive ones and are associated with a range of possible outcomes.Depressive rumination is an emotion regulation strategy involving repetitive negative thinking about oneself, feelings,...

DOI: 10.1037/cps0000343 (opens in new tab) Full text (opens in new tab) Counterpoint Flow mathematics Depressive symptoms Psychoanalysis +1

Meditation and workplace health: a systematic review and meta-analysis of mental and cardiometabolic outcomes among employees

Health Psychology Review April 16, 2026 Mahesh Kumar Khanal, Peter Saunders, Kathy Nguyen et al.

Employees are severely affected by psychological distress, poor cardiometabolic health, and reduced productivity. Meditation has emerged as a potential strategy to enhance overall health. This systematic review synthesised the effectiveness of meditation for improving employees’ mental health and cardiometabolic risk (CMR) markers across 132 randomised controlled trials (145 intervention groups...

DOI: 10.1080/17437199.2026.2652892 (opens in new tab) Anxiety Transcendental meditation Psychological intervention Mental health +8

Adolescent Psychedelic-Assisted Therapy

Acta Psychedelica April 16, 2026 Bryony Insua‐summerhays, Edward Jacobs

Amidst a growing prevalence of adolescent mental ill-health, there is a pressing need to develop effective therapeutic interventions. Despite promising results from adult trials of psychedelic-assisted therapies (P-AT), translating these interventions to adolescents presents challenges. Therapeutic outcomes in paediatric contexts cannot be inferred from adult studies due to age-dependent...

Efficacy and safety evaluation of intravenous esketamine in alleviating perioperative depressive symptoms in Parkinson’s disease: a randomized controlled trial

BMC Anesthesiology April 15, 2026 Wei Tan, Yuanyuan Gao, Dan Su et al.

Depressive symptoms frequently afflict individuals with Parkinson’s disease (PD). The current study was consequently conducted to determine the efficacy of low-dose intravenous esketamine in managing postoperative depressive symptoms, thereby exploring its potential mechanisms of action in PD patients subjected to non-intracranial surgery. In this randomized, double-blind, placebo-controlled...

Detached mindfulness as a stand-alone intervention: a Systematic Review and meta-analysis

Frontiers in Psychiatry April 15, 2026 Samuel G. Myers, Stian Solem

Background Detached Mindfulness (DM) is a central, transdiagnostic technique within Metacognitive Therapy (MCT). It involves increasing meta-awareness of intrusions while decentring from and disengaging with them, and is used to reduce the Cognitive Attentional Syndrome and dysfunctional metacognitive beliefs—key components of the metacognitive model of psychological disorders. Although DM is...

Mindfulness Based Cognitive Therapy for Children And Adolescent: A Systematic Review

Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry April 15, 2026 Hasan Karataş, Emine Sevinç Tok

Mindfulness-Based Cognitive Therapy, developed to prevent depression relapse in adults diagnosed with clinical depression, has attracted the attention of researchers in the current literature, and there is a growing interest in these applications. This growing interest has led to Mindfulness-Based Cognitive Therapy applications for children and adolescents. The current systematic review focuses...

Mindfulness-Based Cognitive Therapy Self-Directed Education in Depressive Symptom Remission: A Quality Improvement Study.

Journal of doctoral nursing practice April 15, 2026 Bethanie Simmons-Becil, Kirsten Pancione

Background: Mindfulness-based cognitive therapy (MBCT), a therapeutic method that combines cognitive behavioral therapy (CBT) techniques and mindful meditation teachings, has been highly efficacious in remission maintenance for depressive symptoms and is currently recommended for remission maintenance of depression. Objective: The MBCT quality improvement study sought to implement an...