Progress in Neuro-Psychopharmacology and Biological Psychiatry
July 1, 2026
Guilherme Lodetti, Rafael Mariano de Bitencourt, Antonio Inserra et al.
BackgroundAlcohol use disorder (AUD) remains difficult to treat with lasting success, leading to growing interest in alternative therapeutic approaches. Psychedelic compounds such as Ayahuasca, a traditional brew used in Indigenous Amazonian ceremonies containing N,N-dimethyltryptamine (DMT) along with monoamine oxidase-inhibiting β-carbolines, have shown promise in reducing addictive...
Neuropsychopharmacology
July 1, 2026
Denis Arikci, Joran Borgulya, Isabelle Straumann et al.
1 citation
Based on its in vitro profile and preliminary evidence, 4-bromo-2,5-dimethoxyphenethylamine (2C-B) may have psychoactive properties that are similar to 3,4-methylenedioxymethamphetamine (MDMA) and psilocybin, which are investigated for the treatment of posttraumatic stress disorder and depressive disorders. We compared acute effects of 2C-B (10, 20, and 30 mg), 125 mg MDMA, and 25 mg psilocybin...
Physical chemistry chemical physics : PCCP
July 1, 2026
W S Clemente Junior, K S Bezerra, E G C Matias et al.
Mental disorders represent a major global health problem, with depression being one of the most prevalent and disabling conditions worldwide. Growing evidence suggests that the serotonergic system, particularly the 5-HT2A receptor, plays an important role in modulating mood and cognitive processes, constituting a key pharmacological target for several psychoactive compounds. In this study, we...
Psychopharmacology
July 1, 2026
Sarah Ann Smith, Haseeb Mohammad, Lik Hang N Lee et al.
Interest in psychedelic drugs has increased rapidly because of their potential therapeutic role in psychiatric disorders. Impairments in the sociocognitive skills needed to build and maintain social relationships are prominent features of many psychiatric and neurodevelopmental disorders. Emerging evidence suggests that compounds such as 3,4-methylenedioxymethamphetamine (MDMA), lysergic acid...
Multidisciplinary Collaborative Journal
July 1, 2026
Érika A. Chillogallo–torres, Marcos D. Calle‐morán, Karen P. Cando–andrade et al.
This research involved a literature review on the recreational, Western medicinal and ethnobotanical uses of hallucinogenic mushrooms. Search engines such as PubMed and Google Scholar, among others, and Boolean operators were used. A total of 60 scientific papers in both Spanish and English were analyzed. Since the 11th century, Japan has recorded the consumption of the butterfly mushroom,...
Revista CienciaUANL
July 1, 2026
Armando Ordaz‐hernández, M. Corona-Ramírez, Israel Jesús Orlando Guerrero
La psilocibina, presente en los “hongos mágicos”, y la 5-MeO-DMT, secretada por el sapo Incilius alvarius, fueron empleadas ancestralmente en rituales espirituales en México. Hoy, la ciencia las reconoce como terapias prometedoras contra depresión, ansiedad, estrés postraumático y adicciones resistentes a tratamientos convencionales. Actúan sobre receptores de serotonina y estimulan la...
Journal of Drug Issues
July 1, 2026
Haley M Hummel, Alexia N Obrochta, David C. R. Kerr et al.
Interest has grown in the effects of psilocybin on mental health, but little is known about its naturalistic use alongside alcohol and its relationship to depression and/or anxiety symptoms. Data from the nationally-representative 2024 National Survey Investigating Hallucinogenic Trends of participants who did ( n = 1234) or did not ( n = 1607) report past-year psilocybin and alcohol co-use...
Human Brain Mapping
July 1, 2026
Lorenzo Pasquini, Jakub Vohryzek, Anira Escrichs et al.
Psilocybin has been shown to induce fast and sustained symptoms improvements across various psychiatric conditions, yet its long-term mechanisms of action are not fully understood. Initial evidence suggests that longitudinal functional and structural brain changes implicate fronto-striatal-thalamic (FST) circuitry, a broad system involved in goal-directed behavior and motivational states. Here,...
International Journal of Integrative Health and Mind-Body Medicine
June 30, 2026
Mahesh Jadhav, S. Mishra, Kalpesh Dattani
Background:-Male infertility is frequently associated with significant psychological distress, including anxiety, depression, and reduced quality of life. Conventional management primarily addresses physiological causes, often neglecting psychosocial dimensions. Yogic interventions may offer a holistic, non-pharmacological approach to address this gap. Case Presentation:-A 27-year-old male...
Humanities and Meditation Research Institute
June 30, 2026
Tae-kyung An
This study aims to analyze research trends in Buddhist counseling-related academic journal articles published in South Korea from 2016 to 2025 and to propose directions for future research. To this end, articles identifiable through domestic academic search services - including KCI, RISS, DBpia, eArticle, and KOAJ - as well as open internet searches were reviewed for publications from 2016...