Background/Objectives: Psilocibin (PSY), a serotonergic hallucinogen, has attracted increasing scientific interest due to its therapeutic potential, particularly in treatment-resistant depression. In parallel with its growing clinical and research relevance, important questions have emerged regarding its safety profile, including potential effects on the liver, kidneys, cardiovascular system,...
Self-referential processing (SRP), the mental activity of linking experiences and stimuli to the self, is fundamental to shaping identity, regulating affect, and navigating complex social environments. Disruptions in SRP are increasingly recognized as a transdiagnostic hallmark across psychiatric disorders, including schizophrenia spectrum disorders, major depressive disorder, and anxiety...
Objetivo: Avaliar a eficácia e a segurança comparativas da psilocibina e do MDMA (3,4-metilenodioximetanfetamina) no tratamento de pacientes com transtorno de estresse pós-traumático (TEPT) e depressão resistente ao tratamento (DRT), com base na evidência disponível de ensaios clínicos randomizados e estudos controlados. Métodos: Revisão sistemática conduzida segundo as diretrizes PRISMA 2020....
The Psilocybe cubensis mushroom is recognized as the primary source of psilocybin in the Americas, occurring naturally across various regions. This fungus has a long history of use in Mesoamerican rituals due to its capacity to induce altered states of consciousness. The defining characteristic of Psilocybe mushrooms is their psilocybin content. Following ingestion, psilocybin is metabolized...
The opening essay of the Turning Toward series sets out the method and the stakes of a philosophy of psychology grounded in testimony and in the analytical psychology of C. G. Jung. Moving from the etymology of agnosticism to Jung's 1959 "I know" and the letters in which he qualified it, the essay places the meditative encounter with the boundary between ego and Self within a long...
Emotional well-being is a fundamental component of overall health, influencing cognitive functioning, interpersonal relationships, productivity, and quality of life. The growing prevalence of psychological distress, including anxiety, depression, stress-related disorders, and emotional dysregulation, has created a pressing need for accessible, effective, and scalable mental health...
Background: Pregnancy is a significant period that brings many changes, both physically and emotionally, as well as psychosocially. This condition often leads to excessive stress in pregnant women. If not addressed, it can impact the health of both the mother and the fetus. One method considered effective for managing stress is Mindfulness-Based Stress Reduction (MBSR). Purpose: To determine...
There is a strong relationship between youth unemployment in Nigeria and psychosocial distress, anxiety, depression, and diminished resilience. Few opportunities for formal mental health services highlight the need for culturally sensitive, accessible, and cost-effective interventions. This systematic review aims to compile evidence on the benefits of mind-body medicine (MBM) interventions...
HEALTH CARE JURNAL KESEHATANJuly 3, 2026Amalia Sania Qonita, Fatimah Azzahroini Rajati, Danuartha Vandika et al.
Depression is one of the most common mental health disorders among adolescents and can affect social functioning, academic performance, and quality of life. One non-pharmacological intervention that can be used to address depression is mindfulness therapy. This article aims to describe changes in depression levels among adolescents after receiving mindfulness therapy. The method used was...
Kuyken et al’s1 individual participant data (IPD) meta-analysis of mindfulness-based cognitive therapy (MBCT) for the prevention of depressive relapse/recurrence has supported MBCT’s dissemination as a frontline treatment for depression. MBCT is now recommended in multiple clinical guidelines including the National Institute for Health and Care Excellence in the United Kingdom and is widely...