Journal of Nursing Practice
October 31, 2020
Linlin Lindayani, Agus Hendra, Lia Juniarni et al.
Background: The elderly are individuals who have entered the age of 60 years (Hurlock, 2004). One of the most common elderly problems that is more commonly found is depression. Currently increasing research and reviews support the efficiency of psychotherapy treatments for depression. Based on traditional interventions Mindfulness Based Stress Reduction (MBSR) therapy is recommended for...
Journal of Psychopharmacology
October 11, 2020
Roger S McIntyre, Nelson B Rodrigues, Orly Lipsitz et al.
19 citations
Background: Individuals meeting criteria for treatment-resistant depression (TRD) are differentially affected by high levels of anxiety symptoms. Aims: There is a need to identify the efficacy of novel rapid-onset treatments in adults with mood disorders and comorbid anxious-distress. Methods: This study included patients with treatment-resistant major depressive disorder (MDD) or bipolar...
Journal of neurosurgical anesthesiology
October 1, 2020
Juan Wang, Qiuhua Zhao, Yang Zhou et al.
Background: Ketamine, a commonly used nonbarbiturate anesthetic drug, possesses antidepressant properties at subanesthetic doses; however, the underlying mechanisms remain unclear. Materials and Methods: The analgesic and antidepressant effects of ketamine were explored using a complete Freund adjuvant (CFA)-induced peripheral inflammatory pain model in vivo. Mice were first divided into sham...
Mindfulness
October 1, 2020
Marleen J. Ter Avest, Corina U. Greven, Marloes J. Huijbers et al.
Abstract Objectives Gaining knowledge of dynamic processes of mechanisms underlying mindfulness-based cognitive therapy (MBCT) for recurrent depression could help to improve treatment efficacy. The current study examined the overall course and week-to-week associations of mindfulness and positive/negative affect during MBCT for recurrent depression. Methods Using data from the MOMENT study, 235...
Neuropsychiatric Disease and Treatment
October 1, 2020
Joanna Szarmach, Wiesław Jerzy Cubała, Adam Włodarczyk et al.
15 citations
INTRODUCTION: Ketamine exhibits antidepressant properties in treatment-resistant depression (TRD) with some concern over its cardiovascular safety and tolerability issues. This paper reports on the cardiovascular safety in short-term intravenous ketamine treatment in TRD inpatients with major depressive disorder (MDD) and bipolar disorder (BP). MATERIALS AND METHODS: The observational study...
October 1, 2020
Laura Musazzi
1 citation
Intranasal esketamine has been recently approved by both the American Food and Drug Administration (FDA) and the European Medicines Agency (EMA) for treatment-resistant depression in adults and will be soon clinically available also in Italy. Esketamine is the (S) enantiomer of ketamine, a non-competitive N-Methyl-D-aspartate (NMDA) glutamate receptor antagonist, introduced in clinics as...
Jurnal Ilmiah Keperawatan Indonesia [JIKI]
September 23, 2020
Siti Latipah, Dewi Prabawati, Wilhelmus Hary Susilo
Acquired Immune Deficiency Syndrome (AIDS) is a group of symptoms that arise due to damage to the human immune system due to infection with the Human Immunodeficiency Virus (HIV). People with HIV will cause stigma in society so that psychosocial problems will arise, one of which is depression. Treatment of depressed patients can be done by non-pharmacological therapy, one of which is...
Frontiers in Psychology
September 23, 2020
Christopher M. Wegemer
Dominant theories of depression position self-concept as a central determinant of psychological functioning, but the relationship between the structure of self-concept and depression has not been extensively explored. The present study investigates the relationship between the structure of the self and psychopathological outcomes (depressive symptoms and neuroticism) with two methodological...
Journal of Affective Disorders
September 23, 2020
Anees Bahji, Gustavo Vazquez, Carlos A. Zarate
404 citations
Background: Ketamine appears to have a therapeutic role in certain mental disorders, most notably depression. However, the comparative performance of different formulations of ketamine is less clear. Objectives: This study aimed to assess the comparative efficacy and tolerability of racemic and esketamine for the treatment of unipolar and bipolar major depression. Design: Systematic review and...
Journal of Clinical Psychopharmacology
September 12, 2020
K. Fluegge
To the Editors: N agele et al 1 have suggested medical utility of nitrous oxide (N2O) for the management of treatment-resistant major depression disorder (trMDD). Their work described basic concepts in N2O administration for the lay psychiatrist as well as the compound's known pharmacology and potential risks from repeated exposure, including N2O-induced inactivation of cobalamin and folate...