Bio Systems
2026
Marco Cavaglià, Jack A Tuszynski
Understanding conscious experience requires looking beyond neuronal circuits alone. We propose that lipid membranes, vicinal water, and cerebrospinal fluid (CSF) form a coherent substrate capable of holographic encoding and coupling to endogenous/exogenous electromagnetic fields (EMF). In what follows: (i) we formulate four postulates (membrane as holographic plate; water as coherence medium;...
Frontiers in Human Neuroscience
2026
Josh Roeloffs, Jack A Tuszynski
Dual-process theory of the brain distinguishes fast, parallel, late-commitment cognition (System 1) from slow, sequential, early-commitment cognition (System 2), yet lacks a mechanistic explanation for how these modes operate or how the brain switches between them. Quantum cognition research demonstrates that human decision-making follows quantum probability models under low confidence and...
Bio Systems
August 1, 2024
Akihiro Nishiyama, Shigenori Tanaka, Jack A Tuszynski
In this paper we propose a control theory of manipulating holograms in Quantum Brain Dynamics (QBD) involving our subjective experiences, i.e. qualia. We begin with the Lagrangian density in QBD and extend our theory to a hierarchical model involving multiple layers covering the neocortex. We adopt reservoir computing approach or morphological computation to manipulate waveforms of holograms...
Journal of Consciousness Studies
June 1, 2022
Marco Cavaglià, E. A. Zizzi, S. Dombrowski et al.
General anaesthesia has been used in medical practice since the mid-nineteenth century, but its pharmacological mechanism of action is still not entirely clear. In a top-down approach, investigations probe smaller and smaller scales to shed light on how anaesthetics disrupt or alter neural activity, ultimately resulting in loss of consciousness. In the past few decades, advances in neuroscience...
Journal of Integrative Neuroscience
December 30, 2020
Jack A Tuszynski
This paper presents a historical overview of quantum physics methodology's development and application to various science fields beyond physics, especially biology and consciousness. Following a successful interpretation of several early 20th century experiments, quantum physics gradually provided a conceptual framework for molecular bonds via quantum chemistry. In recent years individual...
Bio Systems
November 1, 2018
Nadezhda Barvitenko, Alfons Lawen, Muhammad Aslam et al.
Myriads of signaling pathways in a single cell function to achieve the highest spatio-temporal integration. Data are accumulating on the role of electromechanical soliton-like waves in signal transduction processes. Theoretical studies strongly suggest feasibility of both classical and quantum computing involving microtubules. A theoretical study of the role of the complex composed of the...
arXiv Preprint Archive
August 23, 2017
Parisa Zarkeshian, Sourabh Kumar, Jack A Tuszynski et al.
Despite great progress in neuroscience, there are still fundamental unanswered questions about the brain, including the origin of subjective experience and consciousness. Some answers might rely on new physical mechanisms. Given that biophotons have been discovered in the brain, it is interesting to explore if neurons use photonic communication in addition to the well-studied electro-chemical...
Medical Hypotheses
April 1, 2017
Lucio Tonello, Massimo Cocchi, Fabio Gabrielli et al.
The accepted paradigms of mainstream neuropsychiatry appear to be incompletely adequate and in various cases offer equivocal analyses. However, a growing number of new approaches are being proposed that suggest the emergence of paradigm shifts in this area. In particular, quantum theories of mind, brain and consciousness seem to offer a profound change to the current approaches. Unfortunately...
Journal of Integrative Neuroscience
September 1, 2015
Lucio Tonello, Massimo Cocchi, Fabio Gabrielli et al.
Cell membrane's fatty acids (FAs) have been carefully investigated in neurons and platelets in order to study a possible connection to psychopathologies. An important link between the FA distribution and membrane dynamics appears to emerge with the cytoskeleton dynamics. Microtubules (MTs) in particular have been implicated in some recent quantum consciousness models and analyses. The recently...
Journal of Integrative Neuroscience
June 1, 2014
Stuart Hameroff, Travis J A Craddock, Jack A Tuszynski
This paper presents a historical perspective on the development and application of quantum physics methodology beyond physics, especially in biology and in the area of consciousness studies. Quantum physics provides a conceptual framework for the structural aspects of biological systems and processes via quantum chemistry. In recent years individual biological phenomena such as photosynthesis...
Frontiers in Human Neuroscience
2013
István Bókkon, Birendra N. Mallick, Jack A Tuszynski
42 citations
Recently, we proposed a novel biophysical concept regarding on the appearance of brilliant lights during near death experiences (NDEs) (Bókkon and Salari, 2012). Specifically, perceiving brilliant light in NDEs has been proposed to arise due to the reperfusion that produces unregulated overproduction of free radicals and energetically excited molecules that can generate a transient enhancement...