Psychological Medicine
February 5, 2015
F J van der Meer, Eva Velthorst, Genetic Risk And Outcome Of Psychosis (group) Investigators
49 citations
BACKGROUND: Prospective studies on the relationship between course of cannabis use and clinical outcome in patients with non-affective psychotic disorders are inconclusive. The current study examined whether (1) persistent, recently started, discontinued and non-cannabis-using patients with a psychotic disorder differed with regard to illness outcome at 3-year follow-up, and (2) whether timing...
Acta Psychiatrica Scandinavica
January 9, 2015
Andrea M. Auther, Kristin Cadenhead, Ricardo E Carrión et al.
46 citations
OBJECTIVE: Cannabis use has been examined as a predictor of psychosis in clinical high-risk (CHR) samples, but little is known about the impact of other substances on this relationship. METHOD: Substance use was assessed in a large sample of CHR participants (N = 370, mean age = 18.3) enrolled in the multisite North American Prodrome Longitudinal Study Phase 1 project. Three hundred and...
Journal of Psychopharmacology
January 8, 2015
JHP van Wel, DB Spronk, Kim P. C. Kuypers et al.
23 citations
Trait impulsivity has been linked to addiction in humans. It has been suggested that drug users with high trait impulsivity levels are more sensitive to subjective drug intoxication. This study assessed whether subjective response to drugs differs between drug users with normal or high levels of trait impulsivity. Regular drug users (N = 122) received doses of cocaine HCl, cannabis, and placebo...
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie
January 2015
C Patissier, M Akdhar, C Manin et al.
Consultations at pediatric emergency units for acute consciousness alterations is frequent. Miscellaneous causes include cranial trauma, meningoencephalitis, metabolic disorders, drugs, or other intoxications. We report here eight cases of infants who were brought to the emergency division due to acute consciousness failure after accidental ingestion of hashish, confirmed by urinary dosage of...
European Neuropsychopharmacology
January 2015
Sagnik Bhattacharyya, Zerrin Atakan, Rocío Martín‐Santos et al.
Cannabis use can induce acute psychotic symptoms and increase the risk of schizophrenia. Impairments in inhibitory control and processing are known to occur both under the influence of cannabis and in schizophrenia. Whether cannabis-induced impairment in inhibitory processing is related to the acute induction of psychotic symptoms under its influence is unclear. We investigated the effects of...
Neurobiology of Disease
2015
Tiziana Rubino, Pamela Prini, Fabiana Piscitelli et al.
Current concepts suggest that exposure to THC during adolescence may act as a risk factor for the development of psychiatric disorders later in life. However, the molecular underpinnings of this vulnerability are still poorly understood. To analyze this, we investigated whether and how THC exposure in female rats interferes with different maturational events occurring in the prefrontal cortex...
UEL Research Repository
2015
S. Lynch
Rationale: Converging evidence suggests that cannabis use can induce psychosis and is a distinct risk factor for schizophrenia. Taken together with the effects of Tetrahydrocannabinol (THC) on neural systems, dopamine and endocannabinoids it is likely that cannabis use may also produce sub- clinical psychosis-linked changes in a much larger number of regular recreational users; observable in...
Psychological Medicine
January 2015
G N Giordano, H Ohlsson, Kristina Sundquist et al.
Although cannabis abuse (CA) is known to be associated with schizophrenia, the causal nature of this association is unclear, with prodromal effects complicating its interpretation. From Swedish national registry databases, we used a co-relative case-control design with full-sibling, half-sibling and first-cousin comparisons, alongside a general Swedish population sample. Using ICD codes, 5456...
Journal of Psychoactive Drugs
2015
Maayan Nagar, Sharon Rabinovitz
Two studies informed by the terror management health model were conducted to examine the question of how death cognition affects cannabis craving and whether actual cannabis smoking alleviates death cognitions. The first study examined whether priming thoughts of death are associated with subjective cannabis craving among 42 frequent cannabis users randomly assigned to either a mortality...
Progress in Neurology and Psychiatry
2015
Zoë Ellison‐wright, Ben Sessa
7 citations
Hallucinogen persisting perception disorder is a disorder of uncertain aetiology occurring mainly after ‘classical’ hallucinogen use ( ie mescaline, psilocybin, dimethyltryptamine and LSD) use. Here, the authors describe the case of a boy with similar symptoms developing after he reported using cannabis seven times.