The Effects of Peripubertal THC Exposure in Neurodevelopmental Rat Models of Psychopathology
International Journal of Molecular Sciences February 15, 2023 Martina di Bartolomeo, Tibor Stark, Serena di Martino et al. 23 citations
Adolescent exposure to cannabinoids as a postnatal environmental insult may increase the risk of psychosis in subjects exposed to perinatal insult, as suggested by the two-hit hypothesis of schizophrenia. Here, we hypothesized that peripubertal Δ9-tetrahydrocannabinol (aTHC) may affect the impact of prenatal methylazoxymethanol acetate (MAM) or perinatal THC (pTHC) exposure in adult rats. We...