Mexican Journal of Medical Research ICSA
July 5, 2026
Omar Azuara-Antonio, Erika Rubí de la Cruz-Elizaldeb, José Eduardo Carmona-Rodriguez et al.
The Psilocybe cubensis mushroom is recognized as the primary source of psilocybin in the Americas, occurring naturally across various regions. This fungus has a long history of use in Mesoamerican rituals due to its capacity to induce altered states of consciousness. The defining characteristic of Psilocybe mushrooms is their psilocybin content. Following ingestion, psilocybin is metabolized...
Neuropsychiatrie
June 30, 2026
Cielo A Estela-Fernandez, Reem Mohamed Yousif Elsheikh, Dal Bianco Beatrice et al.
Major depressive disorder (MDD) is a heterogeneous, debilitating disorder. A distinct subgroup within the MDD spectrum is identified to have treatment-resistant depression (TRD). There is an impetus to find alternative treatments for TRD to reduce disease burden and improve quality of life. Psychedelics have been used in the treatment of various psychiatric disorders since the 1950s, with...
June 19, 2026
Jules Evans, Christian Jurlando, David Luke et al.
preprint
Sorcery, black magic, and supernatural harm are central to many Amazonian shamanic traditions, yet their role in contemporary Western psychedelic culture has received little systematic empirical attention. Ethnographic work suggests that Western participants in ayahuasca tourism often downplay indigenous sorcery frameworks in favour of psychological or therapeutic interpretations of difficult...
Religions
April 29, 2026
Hengfu Zhu, L H Zhu
This study examines the Vajra Exorcism Dance—commonly known as “Beating the Devils” (tiao buzha)—as performed at Yonghegong Lamasery in Beijing, positioning it as a quintessential example of monastic Nuoxi in which ritual form serves as the active embodiment of doctrinal content. By situating the performance within its historical, religious, and socio-political contexts, this paper argues that...
Zenodo (CERN European Organization for Nuclear Research)
April 3, 2026
Espinoza Patricio
preprint
This article reviews the current clinical evidence for psilocybin and ayahuasca as therapeutic agents, examining data from over 134 registered clinical trials and key publications in the New England Journal of Medicine, JAMA, JAMA Psychiatry, and Nature Neuroscience. The review addresses four dimensions: (1) the state of clinical evidence for psilocybin and ayahuasca in major depression and...
Horizonte
March 31, 2026
Arilton Martins Fonseca, Eliana Rodrigues
O objetivo deste estudo foi comparar a religiosidade entre usuários experientes (com mais de 20 anos de uso ritual de Ayahuasca), iniciantes (com menos de 3 anos), adeptos de um centro daimista, município de Piedade - SP, e não usuários de Ayahuasca. Foi realizado um estudo observacional, descritivo e transversal, do qual participaram 48 pessoas, distribuídas em dois grupos: (a) grupo estudo:...
Frontiers in Pharmacology
March 11, 2026
Katrin Brache, Mauricio Diazgranados
Neuropsychiatric disorders affect nearly one billion people worldwide, yet many existing psychopharmacological treatments are limited by adverse effects, drug interactions, and variable efficacy. Ethnopharmacological knowledge embedded in Indigenous health systems offers important perspectives for understanding mental and neurological distress and for informing future research on central...
March 2, 2026
Rebekah Senānāyaka
preprint
Rationale: Ego-dissolution represents a key therapeutic mechanism in psychedelic-assisted therapy, yet current measurement approaches may inadequately capture its multidimensional nature.Objective: To develop and validate the Multidimensional Ego-Dissolution Assessment (MEDA) and examine substance-specific patterns across classical psychedelics.Methods: Items from three validated scales...
Advances in experimental medicine and biology
2026
Berend Olivier, Jocelien D A Olivier
Major depressive disorder (MDD), including treatment-resistant depression (TRD), is a highly prevalent psychiatric disorder. MDD is associated with severe suffering, burden and large economical costs. Although various conventional antidepressant treatments are available, a large portion of depressed people does not or not adequately respond to the first-line treatments (mostly SSRIs and SNRIs)...
Anthropologica
December 16, 2025
Doriane Sabine Slaghenauffi
La aparición del «turismo chamánico» en algunas comunidades y zonas urbanas shipibo-konibo ha provocado un incremento de las prácticas brujeras vernáculas, ahora integradas en el nuevo contexto sociológico de la comercialización del chamanismo vegetalista local. Este clima provoca ataques de brujería tanto a los chamanes rivales como a los turistas que buscan una experiencia chamánica y...