PeerJ
2022
Alessandro M Varani, Saura R Silva, Simone Lopes et al.
7 citations
Psychotria viridis (Rubioideae: Rubiaceae), popularly known as chacrona, is commonly found as a shrub in the Amazon region and is well-known to produce psychoactive compounds, such as the N,N-dimethyltryptamine (DMT). Together with the liana Banisteropsis caapi, P. viridis is one of the main components of the Amerindian traditional, entheogenic beverage known as ayahuasca. In this work, we...
Frontiers in Pharmacology
2022
Daniel Perkins, Broc A. Pagni, Jerome Sarris et al.
53 citations
Background: Naturalistic and placebo-controlled studies suggest ayahuasca, a potent psychedelic beverage originating from Indigenous Amazonian tradition, may improve mental health, alter personality structure, and reduce alcohol and drug intake. To better understand ayahuasca's therapeutic potential and to identify factors that influence therapeutic efficacy, we conducted a naturalistic,...
Frontiers in Psychiatry
2022
Otto Simonsson, José Carlos Bouso, Florian Kurth et al.
6 citations
Recent research suggests that ayahuasca and its alkaloid-containing ingredients may be helpful in the treatment and prevention of certain movement and neurodegenerative disorders. However, such research is still in its infancy and more studies in normative samples seem necessary to explore effects of ayahuasca on clinically relevant brain structures, such as the corpus callosum. The purpose of...
Frontiers in Behavioral Neuroscience
2022
Maria Lara Porpino de Meiroz Grilo, Geovan Menezes de Sousa, Lilían Andrade Carlos de Mendonça et al.
12 citations
Observational studies of long-term users of ayahuasca, an Amazonian psychedelic brew, suggest an increase in resilience via improvements in emotion and cognition. Ayahuasca has also demonstrated clinical antidepressant effects in human and animal studies; however, its potential prophylactic action in depression has not been previously studied. Therefore, this experimental study sought to...
PLOS global public health
2022
José Carlos Bouso, Óscar Andión, Jerome Sarris et al.
115 citations
Ayahuasca is a plant-based decoction native to Amazonia, where it has a long history of use in traditional medicine. Contemporary ritual use of ayahuasca has been expanding throughout the world for mental health purposes, and for spiritual and personal growth. Although researchers have been conducting clinical trials and observational studies reporting medical and psychological benefits, most...
RCMOS - Revista Científica Multidisciplinar O Saber
November 22, 2021
Robenilson Diniz Alves, Epifanio Fernandes da Silva, Maria Loyse da Silva Fernandes et al.
Depression is a chronic psychiatric illness that causes deep sadness and a strong feeling of hopelessness. In this sense, new therapies are being approached. Ayahuasca tea is an example, a drink made from the vine of the Banisteriopsis caapi.and the leaves of Psycotria viridis often used in religious rituals such as santo-daime, and which has also been shown to be effective in the treatment of...
Journal of Ethnopharmacology
November 22, 2021
Bruno Gianfratti, Ricardo Tabach, Marna Eliana Sakalem et al.
23 citations
Ethnopharmacological relevanceAyahuasca, a psychoactive beverage prepared from Banisteriopsis caapi and Psychotria viridis, is originally used by Amazon-based indigenous and mestizo groups for medicinal and ritualistic purposes. Nowadays, ayahuasca is used in religious and shamanic contexts worldwide, and preliminary evidence from preclinical and observational studies suggests therapeutic...
Travel Medicine and Infectious Disease
November 1, 2021
Sherilyn K. D. Houle, Derek Evans, Caitlin Carter et al.
19 citations
BackgroundAyahuasca is a psychotropic drink made from the Amazonian vine Banisteriopsis caapi. Active components include beta-carboline alkaloids and the hallucinogen N-N-dimethyltryptamine (DMT). This review aimed to identify and summarize the literature on the safety and effectiveness of ayahuasca among recreational users.MethodA comprehensive literature search was done on November 1, 2019 in...
Frontiers in Psychology
October 28, 2021
Bernd Brabec de Mori
15 citations
During the last decades, ayahuasca gained much popularity among non-Indigenous and out-of-Amazonia based populations. In popular culture, it has been advertised as a natural remedy that was discovered by Indigenous peoples ante millennia and that has been used for shamanic healing of all kinds of ailments. This “neo-shamanic,” and often recreational, use of ayahuasca, however, has to be...
Şırnak Üniversitesi İlahiyat Fakültesi Dergisi
October 27, 2021
Nadide Şahin
2 citations
Algı ve durum değişikliğine neden olan halüsinojenik bileşikler içeren psikoaktif bitkilerin binlerce yıldır yerli halklar tarafından ritüellerde kullanıldığı bilinmektedir. Bu bağlamda psikoaktif bir içecek olan ayahuasca eski zamanlardan beri Amazon ormanlarında yaşayan çok sayıda yerli kabilenin dinî, tıbbî, sosyal ve sanatsal yaşamlarında önemli bir yere sahiptir. Ayahuascayı insanın ruhsal...