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Alessandro M Varani

4 papers in the library · 9 citations · publishing 2022-2026

Papers

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Comparative chromosome-scale genomics of the ayahuasca liana Banisteriopsis caapi reveals paleopolyploid ancestry and recent tandem-gene expansions as candidate signatures of ethnovariety differentiation

bioRxiv (Cold Spring Harbor Laboratory) October 16, 2026 Vitor Trinca, Francisco Prosdocimi, Pedro Côrtes et al. preprint

Background: Banisteriopsis caapi is the Amazonian liana that provides the β-carboline-rich vine component of ayahuasca, a traditional Amazonian psychoactive preparation used in Indigenous and ceremonial contexts. The species encompasses culturally recognized ethnovarieties, some differing in stem architecture. Despite its cultural, ecological, and pharmacological importance, B. caapi remains...

Unraveling the organellar genomic landscape of the therapeutic and entheogenic plant Mimosa tenuiflora: insights into genetic, structural, and evolutionary dynamics.

Functional & integrative genomics December 30, 2024 Vitor Trinca, Saura R Silva, João V A Almeida et al.

Mimosa tenuiflora, popularly known as "Jurema-Preta", is a perennial tree or shrub native to the tropical regions of the Americas, particularly among Afro-Brazilian and Indigenous Brazilian communities. Known for producing N,N-Dimethyltryptamine, a psychedelic compound with profound psychological effects, Jurema-Preta has been studied for its therapeutic potential in mental health. This study...

DOI: 10.1007/s10142-024-01511-y (opens in new tab) Full text (opens in new tab) DMT Psychoactive compounds Legume evolution Alternative mtdna arrangements +5

The mitogenomic landscape of Banisteriopsis caapi (Malpighiaceae), the sacred liana used for ayahuasca preparation.

Genetics and molecular biology 2024 Edisson Chavarro-Mesa, João Victor Dos Anjos Almeida, Saura R Silva et al. 2 citations

The sacred ayahuasca brew, utilized by indigenous communities in the Amazon and syncretic religious groups in Brazil, primarily consists of a decoction of two plants: (i) the Amazonian liana known as Mariri or Jagube (Banisteriopsis caapi), and (ii) the shrub referred as Chacrona or Rainha (Psychotria viridis). While Chacrona leaves are rich in N,N-Dimethyltryptamine (DMT), a potent...

DOI: 10.1590/1678-4685-gmb-2023-0301 (opens in new tab) Full text (opens in new tab) Psychedelics Genetics Amazonian plants Ethnobotany +1

The complete organellar genomes of the entheogenic plant Psychotria viridis (Rubiaceae), a main component of the ayahuasca brew.

PeerJ 2022 Alessandro M Varani, Saura R Silva, Simone Lopes et al. 7 citations

Psychotria viridis (Rubioideae: Rubiaceae), popularly known as chacrona, is commonly found as a shrub in the Amazon region and is well-known to produce psychoactive compounds, such as the N,N-dimethyltryptamine (DMT). Together with the liana Banisteropsis caapi, P. viridis is one of the main components of the Amerindian traditional, entheogenic beverage known as ayahuasca. In this work, we...

DOI: 10.7717/peerj.14114 (opens in new tab) Full text (opens in new tab) Chacrona Chloroplast Comparative genomics Entheogen +8