Ioannis Iliakis, Maria Anagnostouli, George P Chrousos
BACKGROUND Multiple sclerosis (MS) is a chronic inflammatory disease affecting the central nervous system, often leading to poor sleep quality and diminished quality of life (QoL) for affected patients. Sleep disturbances in MS do not always correlate linearly with other symptoms such as anxiety, depression, fatigue, or pain. Various approaches, including stress reduction techniques such as...
Minjung Kim, Jin Young Park, Sehwan Park et al.
BACKGROUND Pregnancy is a vulnerable period for women, exposing them to various mental health issues such as depression and anxiety. The perinatal period is particularly crucial because the mother's mental health significantly affects the mother’s physical health, pregnancy outcomes, fetal development, postnatal outcomes, and infant development. Psychotherapeutic approaches for depression are...
Mingyang Zhou, Jingyi Jiang, Zenan Liu et al.
preprint
Background: Mindfulness-Based Cognitive Therapy (MBCT) has demonstrated efficacy in preventing depression relapse and alleviating residual symptoms. However, evidence for its effectiveness in patients currently experiencing depressive episodes—particularly when delivered online—remains limited. This study evaluated the therapeutic effects and dynamic symptom-level mechanisms of online MBCT in...
Jan Wardęszkiewicz, Paweł Holas
preprint
Abstract Mindfulness-Based Cognitive Therapy (MBCT) has demonstrated its effectiveness in preventing depression relapse and reducing symptoms of depression and anxiety. Preliminary research on the online version of an eight-week MBCT (iMBCT) has shown promising results in decreasing emotional distress, aligning with the positive effects observed in traditional MBCT programs. However, there is a...
Shima Shahyad, Reza Mohammadzadeghan, Seyed Hassan Saadat et al.
preprint
Abstract Background The current trial aimed to assess the effectiveness of Mindfulness-Based Stress Reduction training on the level of mental health, salivary cortisol and α-amylase levels of students. Methods This research was an experimental trial with a pre-test-post-test design and a control group. The statistical population of the research included all students studying in the universities...
Arina Qona’ah, Moses Glorino Rumambo Pandin, Nursalam Nursalam
preprint
ABSTRACT Most diabetes mellitus patients experience psychological problems resulting from the disease, disease management, and complications. Inadequate management of psychological problems may place patients at greater risk for depression. This systematic review aims to identify the effects of mindful interventions in controlling glycemic levels and psychological well-being in diabetes...
Chetan Bahadur Kathayat
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Purpose: This review aims to explore the effectiveness of mindfulness meditation in promoting mental health and improving academic performance among students.Methods: Studies examining the impact of mindfulness meditation on students' mental well-being and academic outcomes were reviewed and analyzed. Various aspects such as memory, focus, concentration, and overall academic performance were...
Yongxin Luo, Yaoyao Zhang, Yuqing Zhai et al.
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Abstract Our study seeks to investigate the neural mechanisms underlying brief mindfulness meditation through the utilization of electroencephalogram (EEG) recordings and machine learning techniques. Twenty-four participants underwent mindfulness training, with pre- and post-practice physiological assessments and EEG recordings. Deep learning was used to analyze EEG data to predict mindfulness...
Matt Butler, Ellen Moore, James Rucker et al.
preprint
Abstract Hallucinogen persisting perceptual disorder (HPPD) is characterised by episodes of altered perception linked to past psychoactive drug use, accompanied by distress and functional impairment. To date, clinical characterisation has been limited in scale. Using TriNetX, a global federated health research network of electronic health records, we conducted a retrospective cohort study...
Paul Glue, Colleen Loo, Johnson Fam et al.
preprint
Abstract Ketamine has rapid-onset antidepressant activity in patients with treatment-resistant major depression (TRD). The safety and tolerability of racemic ketamine may be improved if given orally, as an extended release tablet (R-107), compared with other routes of administration. In this phase 2 multicentre clinical trial, adult patients with TRD and Montgomery-Asberg Depression Rating...