Frontiers in Behavioral Neuroscience
July 22, 2011
C. Zanettini, Leigh V Panlilio, M. Aliczki et al.
Cannabis has long been known to produce cognitive and emotional effects. Research has shown that cannabinoid drugs produce these effects by driving the brain’s endogenous cannabinoid system and that this system plays a modulatory role in many cognitive and emotional processes. This review focuses on the effects of endocannabinoid system modulation in animal models of cognition (learning and...
July 17, 2011
Erin Koffel
3 citations
This study examined the reliability and validity of an expanded version of the Iowa Sleep Disturbances Inventory (ISDI; Koffel & Watson, 2010) in 2 samples (219 college students and 200 psychiatric patients). The expanded ISDI includes the scales of Sleep Paralysis and Sleep Hallucinations. These scales, along with the Nightmares scale, help define a higher order factor entitled Unusual Sleep...
Alzheimer s & Dementia
July 1, 2011
Márcio Luiz Figueredo Balthazar, Tátila Martins Lopes, Ana Carolina Coan et al.
Dysfunction of brain's Default Mode Network (DMN) has been increasingly described in patients with neurodegenerative diseases, but little is known about DMN's intrinsic functional connectivity (IFC) in Posterior Cortical Dysfunction (PCD) syndrome. We report a 56 year-old woman with PCD syndrome (MMSE = 24, CDR = 0.5) with visuospatial and anxiety complaints, confirmed by neuropsychological...
Journal of basic and clinical physiology and pharmacology
June 17, 2011
Tatiana Bregman, Ester Fride
Substantial data have been accumulated regarding the molecular basis of cystic fibrosis (CF) pathogenesis, whereas the influence of biochemical impairments on brain processes has been the focus of much less attention. We have studied some behavioral parameters, such as motor activity and anxiety level, in a mice model of CF. We have assumed that functioning of the endocannabinoid system could...
Frontiers in Behavioral Neuroscience
June 7, 2011
I. Akirav
Cannabinoid agonists generally have a disruptive effect on memory, learning, and operant behavior that is considered to be hippocampus-dependent. Nevertheless, under certain conditions, cannabinoid receptor activation may facilitate neuronal learning processes. For example, CB1 receptors are essential for the extinction of conditioned fear associations, indicating an important role for this...
Psicooncología
June 1, 2011
Angela Palao, Beatriz Rodríguez, Amador Priede et al.
9 citations
The population of cancer survivors is increasing due to advances in medicine. Achieving an increase in survival is not enough and the focus is on improving the quality of life in all its dimensions, including psychological and spiritual. New psychosocial needs arise in this population. In general, major mental disorders such as major depression or PTSD are rare among survivors, while less...
The International Journal of Neuropsychopharmacology
June 2011
Aurelie A Boucher, Glenn E. Hunt, Jacques Micheau et al.
Cannabis increases the risk of schizophrenia in genetically vulnerable individuals. In this study we aim to show that the schizophrenia susceptibility gene neuregulin 1 (Nrg1) modulates the development of tolerance to cannabinoids in mice. Nrg1 heterozygous (HET) and wild-type (WT) mice were treated daily for 15 d with the synthetic analogue of Δ9-tetrahydrocannabinol, CP55,940 (0.4 mg/kg). We...
Neuropsychopharmacology
June 2011
Toby T Winton-Brown, Paul Allen, Sagnik Bhattacharyya et al.
Although the effects of cannabis on perception are well documented, little is known about their neural basis or how these may contribute to the formation of psychotic symptoms. We used functional magnetic resonance imaging (fMRI) to assess the effects of Delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) during visual and auditory processing in healthy volunteers. In total, 14 healthy...
Journal of Holistic Nursing
June 2011
Cecile A Lengacher, Versie Johnson-Mallard, Michelle Barta et al.
To assess the feasibility of whether mindfulness-based stress reduction (MBSR) has a positive effect on breast cancer survivors' psychological status, psychosocial characteristics, symptoms, and quality of life (QOL) during the critical transition period from end of treatment to resumption of daily activities. Single-group, quasi-experimental, pretest-posttest design. A sample of 19 women who...
Victorian Literature and Culture
May 18, 2011
Beth Tressler
In a letter that she wrote to her childhood governess and religious mentor Maria Lewis in 1839, George Eliot describes a pervading and distressful mental anxiety – one that would come to greatly influence both the constitution and development of her fiction. Still within the throes of her evangelical ardor, Eliot laments in this letter that the “disjointed specimens” of history, poetry,...